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Joseph M Reynolds

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Articles 36
Citations 2330
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Recent Articles
1.
Fresquez A, Hogan J, Rivera P, Patterson K, Singer K, Reynolds J, et al.
J Biol Chem . 2024 May; 300(7):107422. PMID: 38815866
Infiltration of monocyte-derived cells to sites of infection and injury is greater in males than in females, due in part, to increased chemotaxis, the process of directed cell movement toward...
2.
Elhaj R, Reynolds J
Mil Med Res . 2023 Mar; 10(1):11. PMID: 36882803
Gulf War Illness (GWI) encompass a spectrum of maladies specific to troops deployed during the Persian Gulf War (1990-1991). There are several hypothesized factors believed to contribute to GWI, including...
3.
Chang K, Reynolds J, Liu Y, He J
Vaccines (Basel) . 2022 Feb; 10(2). PMID: 35214706
"Bugs as drugs" in medicine encompasses the use of microbes to enhance the efficacy of vaccination, such as the delivery of vaccines by -the protozoan etiological agent of leishmaniasis. This...
4.
Patterson K, Vajdic T, Martinez G, Feller A, Reynolds J
Immune Netw . 2021 Nov; 21(5):e35. PMID: 34796039
Gulf War Veterans' Illnesses (GWI) encompasses a broad range of unexplained symptomology specific to Veterans of the Persian Gulf War. Gastrointestinal (GI) distress is prominent in veterans with GWI and...
5.
Marks K, Cho K, Stickling C, Reynolds J
Immune Netw . 2021 Jul; 21(3):e18. PMID: 34277108
TLR signaling is critical for broad scale immune recognition of pathogens and/or danger molecules. TLRs are particularly important for the activation and the maturation of cells comprising the innate immune...
6.
Marks K, Flaherty S, Patterson K, Stratton M, Martinez G, Reynolds J
Cell Rep . 2021 Jun; 35(13):109303. PMID: 34192530
Pathogenic Th17 cells drive inflammation in autoimmune disease, yet the molecular programming underlying Th17 cell pathogenicity remains insufficiently understood. Activation of Toll-like receptor 2 (TLR2) increases Th17 cell inflammatory potential,...
7.
Peterson T, Jaiswal M, Beaman K, Reynolds J
Front Immunol . 2019 Aug; 10:1911. PMID: 31456807
Proper orchestration of T lymphocyte development is critical, as T cells underlie nearly all responses of the adaptive immune system. Developing thymocytes differentiate in response to environmental cues carried from...
8.
Tanaka K, Martinez G, Yan X, Long W, Ichiyama K, Chi X, et al.
Cell Rep . 2018 May; 23(8):2318-2329. PMID: 29791844
T helper 17 (Th17) cell development is programmed by the orphan nuclear receptor RORγt, but the underlying mechanism is not well understood. Nuclear receptor-mediated transcriptional activation depends on coactivators. Here,...
9.
Young K, Flaherty S, Woodman K, Sharma-Walia N, Reynolds J
J Leukoc Biol . 2017 Aug; 102(5):1229-1235. PMID: 28848043
T cell activation and effector function is characterized by changes in metabolism. Altered metabolism is common to almost all types of activated T cells, but fatty acid synthesis seems to...
10.
Maturu P, Jones D, Ruteshouser E, Hu Q, Reynolds J, Hicks J, et al.
Neoplasia . 2017 Mar; 19(3):237-249. PMID: 28254151
Wilms' tumors (WT), which accountfor 6% of all childhood cancers, arise from dysregulated differentiation of nephrogenic progenitor cells from embryonic kidneys. Though there is an improvement in the prognosis of...