Joseph M Amann
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Explore the profile of Joseph M Amann including associated specialties, affiliations and a list of published articles.
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28
Citations
929
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Recent Articles
1.
Guan S, Suman S, Amann J, Wu R, Carbone D, Wang J, et al.
Neoplasia
. 2022 Aug;
32:100824.
PMID: 35914370
Non-small cell lung cancer (NSCLC) is a heterogeneous disease with genetic and environmental parameters that influence cell metabolism. Because of the complex interplay of environmental factors within the tumor microenvironment...
2.
Wang W, Shulman A, Amann J, Carbone D, Tsichlis P
Semin Cancer Biol
. 2022 Apr;
86(Pt 2):543-554.
PMID: 35398266
Small cell lung cancer (SCLC) is an extremely aggressive neuroendocrine tumor, accounting for approximated 13% of all lung cancer cases. SCLC is characterized by rapid growth and early metastasis. Despite...
3.
Tessari A, Soliman S, Orlacchio A, Capece M, Amann J, Visone R, et al.
J Cancer Metastasis Treat
. 2021 Nov;
6.
PMID: 34778565
Non-small cell lung cancer (NSCLC) remains the leading cause of cancer-related deaths in the Western world. Despite progress made with targeted therapies and immune checkpoint inhibitors, the vast majority of...
4.
Ikarashi D, Okimoto T, Shukuya T, Onagi H, Hayashi T, Sinicropi-Yao S, et al.
JTO Clin Res Rep
. 2021 Oct;
2(10):100230.
PMID: 34647108
Introduction: This study investigates the immune profile of the primary lung tumors and the corresponding brain metastasis from patients with NSCLC using multiplex fluorescence immunohistochemistry. Methods: The study evaluated 34...
5.
Wang W, Shilo K, Amann J, Shulman A, Hojjat-Farsangi M, Mellstedt H, et al.
Cell Death Dis
. 2021 Jun;
12(6):577.
PMID: 34088900
Small cell lung cancer (SCLC) remains a deadly form of cancer, with a 5-year survival rate of less than 10 percent, necessitating novel therapies. Receptor tyrosine kinase-like orphan receptor 1...
6.
Koenig M, Agana B, Kaufman J, Sharpnack M, Wang W, Weigel C, et al.
Cancer Res
. 2021 May;
81(16):4194-4204.
PMID: 34045189
STK11 (liver kinase B1, LKB1) is the fourth most frequently mutated gene in lung adenocarcinoma, with loss of function observed in up to 30% of all cases. Our previous work...
7.
Cerciello F, Choi M, Sinicropi-Yao S, Lomeo K, Amann J, Felley-Bosco E, et al.
Cancer Epidemiol Biomarkers Prev
. 2020 Aug;
29(10):1973-1982.
PMID: 32732250
Background: We have verified a mass spectrometry (MS)-based targeted proteomics signature for the detection of malignant pleural mesothelioma (MPM) from the blood. Methods: A seven-peptide biomarker MPM signature by targeted...
8.
Shukuya T, Ghai V, Amann J, Okimoto T, Shilo K, Kim T, et al.
J Thorac Oncol
. 2020 Jun;
15(11):1773-1781.
PMID: 32565389
Introduction: Anti-programmed cell death protein 1 (PD-1) or programmed death-ligand 1 (PD-L1) antibody therapy is a standard treatment for advanced NSCLC, and PD-L1 immunohistochemistry is used as a predictive biomarker...
9.
Lorch G, Sivaprakasam K, Zismann V, Perdigones N, Contente-Cuomo T, Nazareno A, et al.
Clin Cancer Res
. 2019 Aug;
25(19):5866-5877.
PMID: 31431454
Purpose: Naturally occurring primary canine lung cancers share clinicopathologic features with human lung cancers in never-smokers, but the genetic underpinnings of canine lung cancer are unknown. We have charted the...
10.
The Effect of LKB1 Activity on the Sensitivity to PI3K/mTOR Inhibition in Non-Small Cell Lung Cancer
Shukuya T, Yamada T, Koenig M, Xu J, Okimoto T, Li F, et al.
J Thorac Oncol
. 2019 Mar;
14(6):1061-1076.
PMID: 30825612
Introduction: Liver kinase B1 (LKB1), also called serine/threonine kinase 11 (STK11), is a tumor suppressor that functions as master regulator of cell growth, metabolism, survival, and polarity. Approximately 30% to...