Joseph Heimiller
Overview
Explore the profile of Joseph Heimiller including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
203
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0
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Recent Articles
1.
Sridharan V, Heimiller J, Robida M, Singh R
PLoS One
. 2016 Mar;
11(3):e0150768.
PMID: 26942929
The Drosophila polypyrimidine tract-binding protein (dmPTB or hephaestus) plays an important role during spermatogenesis. The heph2 mutation in this gene results in a specific defect in spermatogenesis, causing aberrant spermatid...
2.
Heimiller J, Sridharan V, Huntley J, Wesley C, Singh R
PLoS One
. 2014 Jul;
9(7):e98585.
PMID: 25014769
The Drosophila polypyrimidine tract-binding protein (dmPTB or hephaestus) plays an important role during embryogenesis. A loss of function mutation, heph(03429), results in varied defects in embryonic developmental processes, leading to...
3.
Schwartz J, Ebmeier C, Podell E, Heimiller J, Taatjes D, Cech T
Genes Dev
. 2012 Dec;
26(24):2690-5.
PMID: 23249733
Mutations in the RNA-binding protein FUS (fused in sarcoma)/TLS have been shown to cause the neurodegenerative disease amyotrophic lateral sclerosis (ALS), but the normal role of FUS is incompletely understood....
4.
Chung E, Heimiller J, Leinwand L
PLoS One
. 2012 Aug;
7(7):e42297.
PMID: 22860109
Background: Although the hypertrophic responses of the heart to pregnancy and exercise are both considered to be physiological processes, they occur in quite different hormonal and temporal settings. In this...
5.
van Bergeijk P, Heimiller J, Uyetake L, Su T
PLoS One
. 2012 Jun;
7(5):e36539.
PMID: 22666323
Tumor suppressor p53 plays a key role in DNA damage responses in metazoa, yet more than half of human tumors show p53 deficiencies. Therefore, understanding how therapeutic genotoxins such as...
6.
Sridharan V, Heimiller J, Singh R
Mol Cell Biol
. 2010 Dec;
31(4):652-61.
PMID: 21149581
The large subunit of the U2 auxiliary factor (U2AF) recognizes the polypyrimidine tract (Py-tract) located adjacent to the 3' splice site to facilitate U2 snRNP recruitment. While U2AF is considered...