Vinod Sridharan
Overview
Explore the profile of Vinod Sridharan including associated specialties, affiliations and a list of published articles.
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5
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50
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Recent Articles
1.
Sridharan V, Heimiller J, Robida M, Singh R
PLoS One
. 2016 Mar;
11(3):e0150768.
PMID: 26942929
The Drosophila polypyrimidine tract-binding protein (dmPTB or hephaestus) plays an important role during spermatogenesis. The heph2 mutation in this gene results in a specific defect in spermatogenesis, causing aberrant spermatid...
2.
Heimiller J, Sridharan V, Huntley J, Wesley C, Singh R
PLoS One
. 2014 Jul;
9(7):e98585.
PMID: 25014769
The Drosophila polypyrimidine tract-binding protein (dmPTB or hephaestus) plays an important role during embryogenesis. A loss of function mutation, heph(03429), results in varied defects in embryonic developmental processes, leading to...
3.
Sridharan V, Heimiller J, Singh R
Mol Cell Biol
. 2010 Dec;
31(4):652-61.
PMID: 21149581
The large subunit of the U2 auxiliary factor (U2AF) recognizes the polypyrimidine tract (Py-tract) located adjacent to the 3' splice site to facilitate U2 snRNP recruitment. While U2AF is considered...
4.
Robida M, Sridharan V, Morgan S, Rao T, Singh R
Proc Natl Acad Sci U S A
. 2010 Jul;
107(28):12570-5.
PMID: 20616016
Although mammalian polypyrimidine tract-binding (PTB) protein functions in most or all cell types to regulate a wide spectrum of transcripts, Drosophila PTB encodes an abundant male germline-specific mRNA isoform (dmPTB)...
5.
Sridharan V, Singh R
Mol Cell Biol
. 2007 Aug;
27(20):7334-44.
PMID: 17709389
Recognition of polypyrimidine (Py) tracts typically present between the branch point and the 3' splice site by the large subunit of the essential splicing factor U2AF is a key early...