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Joseph El Khoury

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Articles 67
Citations 9211
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Recent Articles
1.
Planchon M, Fishman J, El Khoury J
Viruses . 2025 Jan; 16(12. PMID: 39772120
Monocytes are crucial players in innate immunity. The human cytomegalovirus (CMV) infection has significant impacts on monocyte effector functions and gene expression. CMV, a β-herpesvirus, disrupts key monocyte roles, including...
2.
Izzy S, Yahya T, Albastaki O, Cao T, Schwerdtfeger L, Abou-El-Hassan H, et al.
Brain Commun . 2024 Jul; 6(4):fcae147. PMID: 39045090
The associations between human concussions and subsequent sequelae of chronic neuropsychiatric and cardiovascular diseases such as hypertension have been reported; however, little is known about the underlying biological processes. We...
3.
Kassir G, El Hayek S, Charara R, Cherro M, Itani H, El Khoury J
PLOS Glob Public Health . 2023 Mar; 2(12):e0001428. PMID: 36962861
Schizophrenia is a chronic, debilitating mental illness that contributes significantly to the global burden of disease. Assertive outreach treatment for patients with schizophrenia and psychotic disorders has been implemented to...
4.
Whitson H, Colton C, El Khoury J, Gate D, Goate A, Heneka M, et al.
Brain Behav Immun Health . 2022 Sep; 22:100462. PMID: 36118272
Neuroinflammation has been recognized as a component of Alzheimer's Disease (AD) pathology since the original descriptions by Alois Alzheimer and a role for infections in AD pathogenesis has long been...
5.
Nieland L, van Solinge T, Cheah P, Morsett L, El Khoury J, Rissman J, et al.
Mol Ther Oncolytics . 2022 May; 25:121-136. PMID: 35572197
Non-coding RNAs, including microRNAs (miRNAs), support the progression of glioma. miR-21 is a small, non-coding transcript involved in regulating gene expression in multiple cellular pathways, including the regulation of proliferation....
6.
Wu L, Kalish B, Finander B, Cao T, Jin G, Yahya T, et al.
J Neurosci . 2022 Feb; 42(12):2418-2432. PMID: 35105673
Repetitive mild traumatic brain injury (mTBI) in children and adolescents leads to acute and chronic neurologic sequelae and is linked to later life neurodegenerative disease. However, the biological mechanisms connecting...
7.
Maalouf F, Haidar R, Mansour F, Elbejjani M, El Khoury J, Khoury B, et al.
J Affect Disord . 2022 Jan; 302:58-65. PMID: 35085669
Background: On August 4, 2020, Beirut's port experienced one of the strongest non-nuclear explosions in history, killing approximately 200 people, displacing 300,000 persons, and injuring more than 1000 children. Methods:...
8.
Jorge A, Lao T, Kim R, Licciardi S, El Khoury J, Luster A, et al.
J Immunol . 2022 Jan; 208(4):955-967. PMID: 35082161
Deficiency in the clearance of cellular debris is a major pathogenic factor in the emergence of autoimmune diseases. We previously demonstrated that mice deficient for scavenger receptor class F member...
9.
Robles R, Keeley J, Vega-Ramirez H, Cruz-Islas J, Rodriguez-Perez V, Sharan P, et al.
Int J Clin Health Psychol . 2021 Dec; 22(1):100281. PMID: 34934423
Background/objective: The most recent versions of the two main mental disorders classifications-the World Health Organization's ICD-11 and the American Psychiatric Association's DSM-5-differ substantially in their diagnostic categories related to transgender...
10.
Wu L, Chung J, Cao T, Jin G, Edmiston 3rd W, Hickman S, et al.
Cell Death Dis . 2021 Nov; 12(11):1064. PMID: 34753914
Traumatic brain injury (TBI) is a leading cause of death and disability with no specific effective therapy, in part because disease driving mechanisms remain to be elucidated. Receptor interacting protein...