Joseph A McQuail
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Explore the profile of Joseph A McQuail including associated specialties, affiliations and a list of published articles.
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24
Citations
538
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Recent Articles
11.
Hernandez C, McQuail J, Schwabe M, Burke S, Setlow B, Bizon J
eNeuro
. 2018 Jul;
5(3).
PMID: 29971246
Glutamate signaling is essential for the persistent neural activity in prefrontal cortex (PFC) that enables working memory. Metabotropic glutamate receptors (mGluRs) are a diverse class of proteins that modulate excitatory...
12.
Hernandez A, Hernandez C, Campos K, Truckenbrod L, Sakarya Y, McQuail J, et al.
J Gerontol A Biol Sci Med Sci
. 2017 Oct;
73(4):450-458.
PMID: 29040389
Nutritional ketosis is induced by high fat/low carbohydrate dietary regimens, which produce high levels of circulating ketone bodies, shifting metabolism away from glucose utilization. While ketogenic diets (KD) were initially...
13.
Hernandez C, Vetere L, Orsini C, McQuail J, Maurer A, Burke S, et al.
Neurobiol Aging
. 2017 Sep;
60:141-152.
PMID: 28946018
Despite the fact that prefrontal cortex (PFC) function declines with age, aged individuals generally show an enhanced ability to delay gratification, as evident by less discounting of delayed rewards in...
14.
McQuail J, Beas B, Kelly K, Simpson K, Frazier C, Setlow B, et al.
J Neurosci
. 2016 Nov;
36(50):12537-12548.
PMID: 27807032
Significance Statement: Working memory, the ability to hold information "in mind," requires persistent activity of pyramidal neurons in prefrontal cortex (PFC) mediated by NMDA receptor (NMDAR) activation. NMDAR loss in...
15.
McQuail J, Frazier C, Bizon J
Trends Mol Med
. 2015 Jun;
21(7):450-60.
PMID: 26070271
Alterations in inhibitory interneurons contribute to cognitive deficits associated with several psychiatric and neurological diseases. Phasic and tonic inhibition imparted by γ-aminobutyric acid (GABA) receptors regulates neural activity and helps...
16.
McQuail J, Nicolle M
Neurobiol Aging
. 2014 Aug;
36(1):323-33.
PMID: 25086838
Fischer 344 × Brown Norway F1 (F344 × BN-F1) hybrid rats express greater longevity with improved health relative to aging rodents of other strains; however, few behavioral reports have thoroughly...
17.
Banuelos C, Beas B, McQuail J, Gilbert R, Frazier C, Setlow B, et al.
J Neurosci
. 2014 Mar;
34(10):3457-66.
PMID: 24599447
Working memory functions supported by the prefrontal cortex decline in normal aging. Disruption of corticolimbic GABAergic inhibitory circuits can impair working memory in young subjects; however, relatively little is known...
18.
McQuail J, Davis K, Miller F, Hampson R, Deadwyler S, Howlett A, et al.
Neuropharmacology
. 2013 Jan;
70:63-73.
PMID: 23347951
Normal aging may limit the signaling efficacy of certain GPCRs by disturbing the function of specific Gα-subunits and leading to deficient modulation of intracellular functions that subserve synaptic plasticity, learning...
19.
Hua K, Schindler M, McQuail J, Forbes M, Riddle D
PLoS One
. 2013 Jan;
7(12):e52728.
PMID: 23300752
Radiation therapy has proven efficacy for treating brain tumors and metastases. Higher doses and larger treatment fields increase the probability of eliminating neoplasms and preventing reoccurrence, but dose and field...
20.
Blutstein T, Castello M, Viechweg S, Hadjimarkou M, McQuail J, Holder M, et al.
Neurotox Res
. 2012 Nov;
24(1):80-93.
PMID: 23192463
In utero exposure to cigarette smoke has severe consequences for the developing fetus, including increased risk of birth complications and behavioral and learning disabilities later in life. Evidence from animal...