Joseph A LiCausi
Overview
Explore the profile of Joseph A LiCausi including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
738
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0
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Recent Articles
1.
Dubash T, Bardia A, Chirn B, Reeves B, LiCausi J, Burr R, et al.
Breast Cancer Res Treat
. 2023 Jun;
201(1):43-56.
PMID: 37318638
Purpose: Metastatic hormone receptor-positive (HR+) breast cancer initially responds to serial courses of endocrine therapy, but ultimately becomes refractory. Elacestrant, a new generation FDA-approved oral selective estrogen receptor degrader (SERD)...
2.
Medford A, Dubash T, Juric D, Spring L, Niemierko A, Vidula N, et al.
NPJ Precis Oncol
. 2019 Jul;
3:18.
PMID: 31341951
Plasma genotyping identifies potentially actionable mutations at variable mutant allele frequencies, often admixed with multiple subclonal variants, highlighting the need for their clinical and functional validation. We prospectively monitored plasma...
3.
Franses J, Basar O, Kadayifci A, Yuksel O, Choz M, Kulkarni A, et al.
Oncologist
. 2018 Oct;
23(10):1260.
PMID: 30315083
No abstract available.
4.
Kwan T, Bardia A, Spring L, Giobbie-Hurder A, Kalinich M, Dubash T, et al.
Cancer Discov
. 2018 Aug;
8(10):1286-1299.
PMID: 30104333
The multiplicity of new therapies for breast cancer presents a challenge for treatment selection. We describe a 17-gene digital signature of breast circulating tumor cell (CTC)-derived transcripts enriched from blood,...
5.
Drapkin B, George J, Christensen C, Mino-Kenudson M, Dries R, Sundaresan T, et al.
Cancer Discov
. 2018 Feb;
8(5):600-615.
PMID: 29483136
Small cell lung cancer (SCLC) patient-derived xenografts (PDX) can be generated from biopsies or circulating tumor cells (CTC), though scarcity of tissue and low efficiency of tumor growth have previously...
6.
Hong X, Sullivan R, Kalinich M, Kwan T, Giobbie-Hurder A, Pan S, et al.
Proc Natl Acad Sci U S A
. 2018 Feb;
115(10):2467-2472.
PMID: 29453278
A subset of patients with metastatic melanoma have sustained remissions following treatment with immune checkpoint inhibitors. However, analyses of pretreatment tumor biopsies for markers predictive of response, including PD-1 ligand...
7.
Miyamoto D, Lee R, Kalinich M, LiCausi J, Zheng Y, Chen T, et al.
Cancer Discov
. 2018 Jan;
8(3):288-303.
PMID: 29301747
Blood-based biomarkers are critical in metastatic prostate cancer, where characteristic bone metastases are not readily sampled, and they may enable risk stratification in localized disease. We established a sensitive and...
8.
Franses J, Basar O, Kadayifci A, Yuksel O, Choz M, Kulkarni A, et al.
Oncologist
. 2017 Sep;
23(1):121-127.
PMID: 28860411
Background: Recent work has demonstrated early shedding of circulating epithelial cells (CECs) from premalignant intraductal papillary mucinous neoplasms (IPMNs). However, the potential use of CECs as a "liquid biopsy" for...
9.
Kalinich M, Bhan I, Kwan T, Miyamoto D, Javaid S, LiCausi J, et al.
Proc Natl Acad Sci U S A
. 2017 Jan;
114(5):1123-1128.
PMID: 28096363
Circulating tumor cells (CTCs) are shed into the bloodstream by invasive cancers, but the difficulty inherent in identifying these rare cells by microscopy has precluded their routine use in monitoring...
10.
Comaills V, Kabeche L, Morris R, Buisson R, Yu M, Madden M, et al.
Cell Rep
. 2016 Dec;
17(10):2632-2647.
PMID: 27926867
TGF-β secreted by tumor stroma induces epithelial-to-mesenchymal transition (EMT) in cancer cells, a reversible phenotype linked to cancer progression and drug resistance. However, exposure to stromal signals may also lead...