Josef Slavik
Overview
Explore the profile of Josef Slavik including associated specialties, affiliations and a list of published articles.
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23
Citations
675
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Recent Articles
11.
Tylichova Z, Slavik J, Ciganek M, Ovesna P, Krcmar P, Strakova N, et al.
J Cell Biochem
. 2017 Dec;
119(6):4664-4679.
PMID: 29274292
Docosahexaenoic acid (DHA) and sodium butyrate (NaBt) exhibit a number of interactive effects on colon cancer cell growth, differentiation, or apoptosis; however, the molecular mechanisms responsible for these interactions and...
12.
Hofmanova J, Slavik J, Ovesna P, Tylichova Z, Vondracek J, Strakova N, et al.
Eur J Nutr
. 2016 Mar;
56(4):1493-1508.
PMID: 26983609
Purpose: Although beneficial effects of the dietary n-3 docosahexaenoic acid (DHA) or butyrate in colon carcinogenesis have been implicated, the mechanisms of their action are not fully clear. Here, we...
13.
Skender B, Hofmanova J, Slavik J, Jelinkova I, Machala M, Moyer M, et al.
Biochim Biophys Acta
. 2014 Jun;
1841(9):1308-17.
PMID: 24953781
Docosahexaenoic acid (DHA), an n-3 polyunsaturated fatty acid present in fish oil, may exert cytotoxic and/or cytostatic effects on colon cancer cells when applied individually or in combination with some...
14.
Ghossoub R, Lembo F, Rubio A, Gaillard C, Bouchet J, Vitale N, et al.
Nat Commun
. 2014 Mar;
5:3477.
PMID: 24637612
Exosomes are small vesicles that are secreted by cells and act as mediators of cell to cell communication. Because of their potential therapeutic significance, important efforts are being made towards...
15.
Kriz V, Pospichalova V, Masek J, Kilander M, Slavik J, Tanneberger K, et al.
J Biol Chem
. 2013 Nov;
289(2):1128-41.
PMID: 24265322
β-Arrestin is a scaffold protein that regulates signal transduction by seven transmembrane-spanning receptors. Among other functions it is also critically required for Wnt/β-catenin signal transduction. In the present study we...
16.
Horova V, Hradilova N, Jelinkova I, Koc M, Svadlenka J, Brazina J, et al.
FEBS J
. 2013 May;
280(14):3436-50.
PMID: 23678861
Tumour necrosis factor (TNF) related apoptosis inducing ligand (TRAIL), a membrane-bound ligand from the TNF family, has attracted significant attention due to its rather specific and effective ability to induce...
17.
Prochazka L, Koudelka S, Dong L, Stursa J, Goodwin J, Neca J, et al.
Apoptosis
. 2013 Jan;
18(3):286-99.
PMID: 23299931
α-Tocopheryl succinate (α-TOS) is a promising anti-cancer agent due to its selectivity for cancer cells. It is important to understand whether long-term exposure of tumour cells to the agent will...
18.
Hofmanova J, Ciganek M, Slavik J, Kozubik A, Stixova L, Vaculova A, et al.
J Nutr Biochem
. 2011 Jul;
23(6):539-48.
PMID: 21775115
The present study highlights the important association between lipid alterations and differentiation/apoptotic responses in human colon differentiating (FHC) and nondifferentiating (HCT-116) cell lines after their treatment with short-chain fatty acid...
19.
Lanz C, Ledermann M, Slavik J, Idle J
Int J Radiat Biol
. 2010 Dec;
87(4):360-71.
PMID: 21158499
Purpose: The aim of this work was to use metabolomics to evaluate sebum as a source of biomarkers for gamma-radiation exposure in the rat, and potentially in man. Proof of...
20.
Lanz C, Patterson A, Slavik J, Krausz K, Ledermann M, Gonzalez F, et al.
Radiat Res
. 2009 Jul;
172(2):198-212.
PMID: 19630524
Abstract Radiation metabolomics employing mass spectral technologies represents a plausible means of high-throughput minimally invasive radiation biodosimetry. A simplified metabolomics protocol is described that employs ubiquitous gas chromatography-mass spectrometry and...