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Jose Carlos Valle-Casuso

Explore the profile of Jose Carlos Valle-Casuso including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 902
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Recent Articles
1.
Schimmich C, Vabret A, Zientara S, Valle-Casuso J
Viruses . 2025 Jan; 17(1). PMID: 39861793
Equine infectious anemia virus (EIAV) is the simplest described within the family, related to the human immunodeficiency viruses (HIV-1 and HIV-2). There is an important interplay between host cells and...
2.
Angin M, Volant S, Passaes C, Lecuroux C, Monceaux V, Dillies M, et al.
Nat Metab . 2020 Jul; 1(7):704-716. PMID: 32694646
Spontaneous control of human immunodeficiency virus (HIV) is generally associated with an enhanced capacity of CD8 T cells to eliminate infected CD4 T cells, but the molecular characteristics of these...
3.
Mikhailova A, Valle-Casuso J, David A, Monceaux V, Volant S, Passaes C, et al.
J Virol . 2020 May; 94(14). PMID: 32350074
HIV-1 successfully establishes long-term infection in its target cells despite viral cytotoxic effects. We have recently shown that cell metabolism is an important factor driving CD4 T cell susceptibility to...
4.
El-Asmi F, McManus F, Brantis-de-Carvalho C, Valle-Casuso J, Thibault P, Chelbi-Alix M
Cytokine . 2020 Feb; 129:155025. PMID: 32044670
Interferon (IFN) plays a central role in regulating host immune response to viral pathogens through the induction of IFN-Stimulated Genes (ISGs). IFN also enhances cellular SUMOylation and ISGylation, though the...
5.
Valle-Casuso J, Angin M, Volant S, Passaes C, Monceaux V, Mikhailova A, et al.
Cell Metab . 2018 Dec; 29(3):611-626.e5. PMID: 30581119
HIV persists in long-lived infected cells that are not affected by antiretroviral treatment. These HIV reservoirs are mainly located in CD4 T cells, but their distribution is variable in the...
6.
Mikhailova A, Valle-Casuso J, Saez-Cirion A
Adv Exp Med Biol . 2018 Jul; 1075:213-239. PMID: 30030795
The era of antiretroviral therapy has made HIV-1 infection a manageable chronic disease for those with access to treatment. Despite treatment, virus persists in tissue reservoirs seeded with long-lived infected...
7.
Valle-Casuso J, Allouch A, David A, Lenzi G, Studdard L, Barre-Sinoussi F, et al.
J Virol . 2017 Sep; 91(23). PMID: 28931685
HIV-1 infection of noncycling cells, such as dendritic cells (DCs), is impaired due to limited availability of deoxynucleoside triphosphates (dNTPs), which are needed for HIV-1 reverse transcription. The levels of...
8.
White T, Brandariz-Nunez A, Valle-Casuso J, Knowlton C, Kim B, Sawyer S, et al.
Virology . 2014 Jul; 460-461:34-44. PMID: 25010268
SAMHD1 is a human restriction factor that prevents efficient infection of macrophages, dendritic cells and resting CD4+ T cells by HIV-1. Here we explored the antiviral activity and biochemical properties...
9.
Brandariz-Nunez A, Valle-Casuso J, White T, Nguyen L, Bhattacharya A, Wang Z, et al.
Retrovirology . 2013 Nov; 10:131. PMID: 24219908
Background: SAMHD1 is a restriction factor that potently blocks infection by HIV-1 and other retroviruses. We have previously demonstrated that SAMHD1 oligomerizes in mammalian cells by immunoprecipitation. Here we investigated...
10.
Fricke T, Valle-Casuso J, White T, Brandariz-Nunez A, Bosche W, Reszka N, et al.
Retrovirology . 2013 Apr; 10:46. PMID: 23622145
Background: Expression of the cellular karyopherin TNPO3/transportin-SR2/Tnp3 is necessary for HIV-1 infection. Depletion of TNPO3 expression in mammalian cells inhibits HIV-1 infection after reverse transcription but prior to integration. Results:...