Jose-Juan Lopez-Rubio
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Explore the profile of Jose-Juan Lopez-Rubio including associated specialties, affiliations and a list of published articles.
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25
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1215
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Recent Articles
1.
Sene S, Pouye M, Martins R, Diallo F, Mangou K, Bei A, et al.
Front Parasitol
. 2025 Jan;
2():1076759.
PMID: 39816817
The emergence of artemisinin partial resistance (ART-r) in malaria parasites has substantially compromised the efficacy of antimalarial treatments across southeast Asia (SE Asia). The spread of ART-r within the African...
2.
Castellano C, Lacroix L, Mathis E, Prorok P, Hennion M, Lopez-Rubio J, et al.
Nucleic Acids Res
. 2023 Dec;
52(2):660-676.
PMID: 38038269
Various origin mapping approaches have enabled genome-wide identification of origins of replication (ORI) in model organisms, but only a few studies have focused on divergent organisms. By employing three complementary...
3.
Menichelli C, Guitard V, Martins R, Lebre S, Lopez-Rubio J, Lecellier C, et al.
PLoS Comput Biol
. 2021 Apr;
17(4):e1008909.
PMID: 33861755
Long regulatory elements (LREs), such as CpG islands, polydA:dT tracts or AU-rich elements, are thought to play key roles in gene regulation but, as opposed to conventional binding sites of...
4.
Rawat M, Kanyal A, Sahasrabudhe A, Vembar S, Lopez-Rubio J, Karmodiya K
Sci Rep
. 2021 Jan;
11(1):852.
PMID: 33441725
Plasmodium falciparum has evolved resistance to almost all front-line drugs including artemisinin, which threatens malaria control and elimination strategies. Oxidative stress and protein damage responses have emerged as key players...
5.
Gurung P, Gomes A, Martins R, Juranek S, Alberti P, Mbang-Benet D, et al.
Cell Microbiol
. 2020 Dec;
23(4):e13303.
PMID: 33340385
Guanine-quadruplexes (G4s) are non-canonical DNA structures that can regulate key biological processes such as transcription, replication and telomere maintenance in several organisms including eukaryotes, prokaryotes and viruses. Recent reports have...
6.
Bouyer G, Barbieri D, Dupuy F, Marteau A, Sissoko A, NDri M, et al.
Commun Biol
. 2020 Dec;
3(1):726.
PMID: 33262483
To ensure the transport of nutrients necessary for their survival, Plasmodium falciparum parasites increase erythrocyte permeability to diverse solutes. These new permeation pathways (NPPs) have been extensively characterized in the...
7.
Lozano-Amado D, Avila-Lopez P, Hernandez-Montes G, Briseno-Diaz P, Vargas M, Lopez-Rubio J, et al.
Int J Parasitol
. 2020 Aug;
50(12):1011-1022.
PMID: 32822677
Epigenetic mechanisms such as histone acetylation and deacetylation participate in regulation of the genes involved in encystation of Entamoeba invadens. However, the histones and target residues involved, and whether the...
8.
Gazanion E, Lacroix L, Alberti P, Gurung P, Wein S, Cheng M, et al.
PLoS Genet
. 2020 Jul;
16(7):e1008917.
PMID: 32628663
Mechanisms of transcriptional control in malaria parasites are still not fully understood. The positioning patterns of G-quadruplex (G4) DNA motifs in the parasite's AT-rich genome, especially within the var gene...
9.
Neveu G, Richard C, Dupuy F, Behera P, Volpe F, Subramani P, et al.
Blood
. 2020 Jun;
136(12):1381-1393.
PMID: 32589714
Plasmodium falciparum gametocytes, the sexual stage responsible for malaria parasite transmission from humans to mosquitoes, are key targets for malaria elimination. Immature gametocytes develop in the human bone marrow parenchyma,...
10.
Vergnes B, Gazanion E, Mariac C, du Manoir M, Sollelis L, Lopez-Rubio J, et al.
J Antimicrob Chemother
. 2019 Aug;
74(11):3231-3239.
PMID: 31365085
Background: For almost a century, antimonials have remained the first-line drugs for the treatment of leishmaniasis. However, little is known about their mode of action and clinical resistance mechanisms. Objectives:...