Jorn Skavland
Overview
Explore the profile of Jorn Skavland including associated specialties, affiliations and a list of published articles.
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23
Citations
263
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Recent Articles
1.
Rim S, Sakkestad S, Zhou F, Gullaksen S, Skavland J, Chauhan S, et al.
Eur J Immunol
. 2023 Apr;
53(8):e2250254.
PMID: 37102399
Enterotoxigenic Escherichia coli (ETEC) is an important cause of children's and travelers' diarrhea, with no licensed vaccine. This study aimed to explore the role of cellular immunity in protection against...
2.
Tislevoll B, Hellesoy M, Fagerholt O, Gullaksen S, Srivastava A, Birkeland E, et al.
Nat Commun
. 2023 Mar;
14(1):1767.
PMID: 36997540
No abstract available.
3.
Tislevoll B, Hellesoy M, Fagerholt O, Gullaksen S, Srivastava A, Birkeland E, et al.
Nat Commun
. 2023 Jan;
14(1):115.
PMID: 36611026
Aberrant pro-survival signaling is a hallmark of cancer cells, but the response to chemotherapy is poorly understood. In this study, we investigate the initial signaling response to standard induction chemotherapy...
4.
Anandan S, Thomsen L, Gullaksen S, Abdelaal T, Kleinmanns K, Skavland J, et al.
Cancers (Basel)
. 2021 Mar;
13(4).
PMID: 33670410
Improved molecular dissection of the tumor microenvironment (TME) holds promise for treating high-grade serous ovarian cancer (HGSOC), a gynecological malignancy with high mortality. Reliable disease-related biomarkers are scarce, but single-cell...
5.
Tadele D, Robertson J, Crispin R, Herrera M, Chlubnova M, Piechaczyk L, et al.
J Biol Chem
. 2020 Dec;
296:100179.
PMID: 33303632
Breakpoint Cluster Region-Abelson kinase (BCR-Abl) is a driver oncogene that causes chronic myeloid leukemia and a subset of acute lymphoid leukemias. Although tyrosine kinase inhibitors provide an effective treatment for...
6.
Sakkestad S, Skavland J, Hanevik K
J Immunol Methods
. 2019 Oct;
476:112673.
PMID: 31629741
A potential hurdle when applying mass cytometry to the field study setting is the streamlining of sample collection while at the same time protecting the integrity of important cell epitopes....
7.
Gullaksen S, Bader L, Hellesoy M, Sulen A, Fagerholt O, Engen C, et al.
Cytometry A
. 2019 Apr;
95(7):792-796.
PMID: 30964237
We describe here a simple and efficient antibody titration approach for cell-surface markers and intracellular cell signaling targets for mass cytometry. The iterative approach builds upon a well-characterized backbone panel...
8.
Reikvam H, Skavland J, Gullaksen S, Hovland R, Gedde-Dahl T, Bruserud O, et al.
Case Rep Hematol
. 2018 Oct;
2018:2045985.
PMID: 30345125
Chronic myeloid leukemia (CML) is a myeloproliferative disorder in which neoplastic cells exhibit the Philadelphia chromosome and the related oncoprotein . Allogeneic stem cell transplantation (allo-SCT) was considered the first-line...
9.
Nepstad I, Hatfield K, Aasebo E, Hernandez-Valladares M, Brenner A, Bartaula-Brevik S, et al.
Expert Opin Ther Targets
. 2018 Jun;
22(7):639-653.
PMID: 29889583
Objectives: Constitutive signaling through the phosphatidylinositol-3-kinase-Akt-mammalian target of rapamycin (PI3K-Akt-mTOR) pathway is present in acute myeloid leukemia (AML) cells. The aim of the study was to compare constitutive PI3K-Akt-mTOR activation...
10.
Gullaksen S, Skavland J, Gavasso S, Tosevski V, Warzocha K, Dumrese C, et al.
Haematologica
. 2017 May;
102(8):1361-1367.
PMID: 28522574
Monitoring of single cell signal transduction in leukemic cellular subsets has been proposed to provide deeper understanding of disease biology and prognosis, but has so far not been tested in...