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Jorgen Isgaard

Explore the profile of Jorgen Isgaard including associated specialties, affiliations and a list of published articles. Areas
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Articles 72
Citations 1520
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Recent Articles
1.
Walser M, Karlsson L, Motalleb R, Isgaard J, Kuhn H, Svensson J, et al.
Sci Rep . 2024 Oct; 14(1):25464. PMID: 39462081
The beneficial effects of exercise are partly mediated via local or systemic functions of the insulin-like growth factor-1 (IGF-1) system. As IGF-1 increases local brain hemoglobin beta (Hbb) transcripts, we...
2.
Wall A, Henriksson M, Nyberg J, Holmgren K, Isgaard J, Lennartsson A, et al.
J Affect Disord . 2024 May; 360:5-14. PMID: 38777273
Background: Exercise interventions show promise in the treatment of anxiety disorders, but effects on health-related quality of life (HR-QoL), work ability, and sick leave are little studied. We investigated these...
3.
Gadd G, Aberg D, Wall A, Zetterberg H, Blennow K, Jood K, et al.
Int J Mol Sci . 2024 May; 25(9). PMID: 38732147
Both high serum insulin-like growth factor-binding protein-1 (s-IGFBP-1) and insulin resistance (IR) are associated with poor functional outcome poststroke, whereas overweight body mass index (BMI; 25-30) is related to fewer...
4.
Walser M, Karlsson L, Motalleb R, Isgaard J, Kuhn H, Aberg N
Heliyon . 2024 Jan; 10(1):e23343. PMID: 38163098
Haemoglobin beta () and delta-aminolevulinate synthase 2 () messenger RNA (mRNA) is mainly found in immature red blood cells, reticulocytes, and not in mature erythrocytes. However, these are also expressed...
5.
Aberg D, Gadd G, Jood K, Redfors P, Stanne T, Isgaard J, et al.
Int J Mol Sci . 2023 Jun; 24(11). PMID: 37298072
Insulin-like growth factor-binding protein-1 (IGFBP-1) regulates insulin-like growth factor-I (IGF-I) bioactivity, and is a central player in normal growth, metabolism, and stroke recovery. However, the role of serum IGFBP-1 (s-IGFBP-1)...
6.
Sanchez-Bezanilla S, Beard D, Hood R, Aberg N, Crock P, Walker F, et al.
Neural Plast . 2022 Apr; 2022:9983042. PMID: 35465399
Aims: We have shown that growth hormone (GH) treatment poststroke increases neuroplasticity in peri-infarct areas and the hippocampus, improving motor and cognitive outcomes. We aimed to explore the mechanisms of...
7.
Wall A, Anger O, Jood K, Blomstrand C, Andreasson U, Blennow K, et al.
Neurol Res . 2021 Jul; 43(12):1013-1022. PMID: 34253146
: While granulocyte colony-stimulating factor (G-CSF) has shown beneficial effects in experimental ischemic stroke (IS), these effects have not been reproduced clinically. Small-to-medium-sized observational studies have reported varying associations for...
8.
Aberg D, Aberg N, Jood K, Redfors P, Blomstrand C, Isgaard J, et al.
Life (Basel) . 2021 Jun; 11(6). PMID: 34072372
Insulin-like growth factor-II (IGF-II) regulates prenatal brain development, but the role in adult brain function and injury is unclear. Here, we determined whether serum levels of IGF-II (s-IGF-II) are associated...
9.
DAssante R, Arcopinto M, Rengo G, Salzano A, Walser M, Gambino G, et al.
ESC Heart Fail . 2021 Jan; 8(2):1681-1686. PMID: 33512777
Aims: Limited data are available regarding cardiac expression of molecules involved in heart failure (HF) pathophysiology. The majority of the studies have focused on end-stage HF with reduced ejection fraction...
10.
Walser M, Svensson J, Karlsson L, Motalleb R, Aberg M, Kuhn H, et al.
Front Endocrinol (Lausanne) . 2021 Jan; 11:606089. PMID: 33488521
In recent years, evidence for hemoglobin (Hb) synthesis in both animal and human brains has been accumulating. While circulating Hb originating from cerebral hemorrhage or other conditions is toxic, there...