Jorge Martin-Perez
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Explore the profile of Jorge Martin-Perez including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
509
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Recent Articles
11.
Sanchez-Bailon M, Calcabrini A, Gomez-Dominguez D, Morte B, Martin-Forero E, Gomez-Lopez G, et al.
Cell Signal
. 2012 May;
24(6):1276-86.
PMID: 22570868
SFKs are frequently deregulated in cancer where they control cellular proliferation, migration, survival and metastasis. Here we study the role of SFKs catalytic activity in triple-negative/basal-like and metastatic human breast...
12.
Tarrega C, Nunes-Xavier C, Cejudo-Marin R, Martin-Perez J, Pulido R
Methods Mol Biol
. 2010 Sep;
661:305-21.
PMID: 20811991
Signaling through MAPK pathways involves a network of activating kinases and inactivating phosphatases. While single MAPK kinases account for specific activation of the distinct MAPKs, inactivation of MAPKs by phosphatases...
13.
MacPherson M, Molina P, Souchelnytskyi S, Wernstedt C, Martin-Perez J, Portillo F, et al.
Mol Biol Cell
. 2009 Nov;
21(2):244-53.
PMID: 19923321
Snail1 is a major factor for epithelial-mesenchymal transition (EMT), an important event in tumor metastasis and in other pathologies. Snail1 is tightly regulated at transcriptional and posttranscriptional levels. Control of...
14.
Garcia-Martinez J, Calcabrini A, Gonzalez L, Martin-Forero E, Agullo-Ortuno M, Simon V, et al.
Cell Signal
. 2009 Nov;
22(3):415-26.
PMID: 19892015
The cytokine prolactin (PRL) plays important roles in the proliferation and differentiation of the mammary gland and it has been implicated in tumorigenesis. The prolactin receptor (PRLR) is devoid of...
15.
Ferrandiz N, Martin-Perez J, Blanco R, Donertas D, Weber A, Eilers M, et al.
DNA Repair (Amst)
. 2009 Jan;
8(3):390-9.
PMID: 19150257
p21(Waf1) (p21) was described as a cyclin-dependent kinase inhibitor, but other p21 activities have subsequently been described, including its ability to inhibit apoptosis in some models. Comparative work on the...
16.
Gonzalez L, Agullo-Ortuno M, Garcia-Martinez J, Calcabrini A, Gamallo C, Palacios J, et al.
J Biol Chem
. 2006 May;
281(30):20851-20864.
PMID: 16728403
To study the role of c-Src in breast cancer tumorigenesis, we generated a cell line derived from MCF7 carrying an inducible dominant negative c-Src (c-SrcDN: K295M/Y527F) under tetracycline control (Tet-On...
17.
Calcabrini A, Garcia-Martinez J, Gonzalez L, Tendero M, Ortuno M, Crateri P, et al.
Carcinogenesis
. 2006 Apr;
27(8):1699-712.
PMID: 16624827
Lauryl gallate is an antioxidant food additive showing low toxicity to normal cells. Here, its antiproliferative effect has been studied on three human breast cancer cell lines: estrogen-dependent, wild-type p53,...
18.
Salinas M, Wang J, Sagarra M, Martin D, Rojo A, Martin-Perez J, et al.
FEBS Lett
. 2004 Dec;
578(1-2):90-4.
PMID: 15581622
Heme oxygenase-1 (HO-1) is a stress response protein that protects cells against diverse noxious stimuli. Although regulation of HO-1 occurs mainly at the transcriptional level, its posttranslational modifications remain unexplored....
19.
Dominguez-Caceres M, Garcia-Martinez J, Calcabrini A, Gonzalez L, Porque P, Leon J, et al.
Oncogene
. 2004 Aug;
23(44):7378-90.
PMID: 15286700
Stimulation of resting W53 cells (lymphoid murine cells expressing prolactin (PRL) receptor) by PRL induced expression of growth-related immediate-early genes (IEG), and proliferation through activation of the Src kinases. Since...
20.
Sarrio D, Perez-Mies B, Hardisson D, Moreno-Bueno G, Suarez A, Cano A, et al.
Oncogene
. 2004 Apr;
23(19):3272-83.
PMID: 15077190
Accumulating evidences indicate that p120 catenin, a member of the E-cadherin (E-CD)/catenin adhesion complex, plays a role in tumor invasion. To establish the expression pattern of p120 in breast cancer,...