Jorge Martin-Perez
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Explore the profile of Jorge Martin-Perez including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
509
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Recent Articles
1.
Mayoral-Varo V, Sanchez-Bailon M, Calcabrini A, Garcia-Hernandez M, Frezza V, Martin M, et al.
Cancers (Basel)
. 2021 Feb;
13(3).
PMID: 33530373
The role of Src family kinases (SFKs) in human tumors has been always associated with tyrosine kinase activity and much less attention has been given to the SH2 and SH3...
2.
Alcala S, Mayoral-Varo V, Ruiz-Canas L, Lopez-Gil J, Heeschen C, Martin-Perez J, et al.
Int J Mol Sci
. 2020 Dec;
21(23).
PMID: 33287468
The authors recently reported on the potential of targeting SRC kinase signaling in pancreatic cancer stem cells [...].
3.
Alcala S, Mayoral-Varo V, Ruiz-Canas L, Lopez-Gil J, Heeschen C, Martin-Perez J, et al.
Int J Mol Sci
. 2020 Oct;
21(20).
PMID: 33050159
The proto-oncogene nonreceptor tyrosine-protein kinase is a member of the family of tyrosine kinases (SFKs), and its activation and overexpression have been shown to play a protumorigenic role in multiple...
4.
Mayoral-Varo V, Calcabrini A, Sanchez-Bailon M, Martinez-Costa O, Gonzalez-Paramos C, Ciordia S, et al.
PLoS One
. 2020 Jul;
15(7):e0235850.
PMID: 32673341
Deregulation of Src kinases is associated with cancer. We previously showed that SrcDN conditional expression in MCF7 cells reduces tumorigenesis and causes tumor regression in mice. However, it remained unclear...
5.
Mayoral-Varo V, Calcabrini A, Sanchez-Bailon M, Martin-Perez J
PLoS One
. 2017 Nov;
12(11):e0188637.
PMID: 29182685
miR205 has a dual activity, as tumor suppressor and as oncogene. Here we analyzed the impact of miR205 ectopic expression in the initial tumorigenic processes of SUM159PT, a triple negative...
6.
da Silva I, Montero-Montero L, Martin-Villar E, Martin-Perez J, Sainz B, Renart J, et al.
Sci Rep
. 2017 Jul;
7(1):6276.
PMID: 28740236
Qa-2 is believed to mediate a protective immune response against cancer; however, little is known about the role of Qa-2 in tumorigenesis. Here, we used 4T1 breast cancer cells to...
7.
Sanchez-Bailon M, Calcabrini A, Mayoral-Varo V, Molinari A, Wagner K, Perez Losada J, et al.
Oncotarget
. 2015 May;
6(15):13520-38.
PMID: 25980494
SFKs are involved in tumorigenesis and metastasis. Here we analyzed c-Src contribution to initial steps of metastasis by tetracycline-dependent expression of a specific shRNA-c-Src, which suppressed c-Src mRNA and protein...
8.
Martin-Perez J, Garcia-Martinez J, Sanchez-Bailon M, Mayoral-Varo V, Calcabrini A
Adv Exp Med Biol
. 2014 Dec;
846:163-88.
PMID: 25472538
Prolactin (PRL) is a polypeptide hormone/cytokine mainly synthesized by the lactotrophic cells of the adenohypophysis. In addition to the best-known role in mammary gland development and the functional differentiation of...
9.
Torres-Ayuso P, Daza-Martin M, Martin-Perez J, Avila-Flores A, Merida I
Oncotarget
. 2014 Oct;
5(20):9710-26.
PMID: 25339152
Diacylglycerol kinase (DGK)α converts diacylglycerol to phosphatidic acid. This lipid kinase sustains survival, migration and invasion of tumor cells, with no effect over untransformed cells, suggesting its potential as a...
10.
Nunes-Xavier C, Martin-Perez J, Elson A, Pulido R
Biochim Biophys Acta
. 2013 Jun;
1836(2):211-26.
PMID: 23756181
Breast cancer is linked to hyperactivation of protein tyrosine kinases (PTKs), and recent studies have unveiled that selective tyrosine dephosphorylation by protein tyrosine phosphatases (PTPs) of specific substrates, including PTKs,...