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Jorge Lopez-Tello

Explore the profile of Jorge Lopez-Tello including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 492
Followers 0
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Recent Articles
1.
Sandovici I, Knee O, Lopez-Tello J, Shreeve N, Fowden A, Sferruzzi-Perri A, et al.
Dis Model Mech . 2024 Aug; 17(8). PMID: 39207227
The placenta is a gatekeeper between the mother and fetus, adapting its structure and functions to support optimal fetal growth. Studies exploring adaptations of placentae that support the development of...
2.
Lopez-Tello J, Kiu R, Schofield Z, Zhang C, Van Sinderen D, Le Gall G, et al.
Mol Metab . 2024 Aug; 88:102004. PMID: 39127167
Background: Recent advances have significantly expanded our understanding of the gut microbiome's influence on host physiology and metabolism. However, the specific role of certain microorganisms in gestational health and fetal...
3.
Zaugg J, Lopez-Tello J, Musial B, Vaughan O, Fowden A, Albrecht C, et al.
Cell Mol Life Sci . 2024 Mar; 81(1):151. PMID: 38526599
Obesity and gestational diabetes (GDM) impact fetal growth during pregnancy. Iron is an essential micronutrient needed for energy-intense feto-placental development, but if mis-handled can lead to oxidative stress and ferroptosis...
4.
Lopez-Tello J, Sferruzzi-Perri A
Methods Mol Biol . 2024 Mar; 2781:1-13. PMID: 38502438
The mouse is a common animal species used for translational studies. In reproductive studies, this animal is typically preferred over other models as the rodent placenta shows similarities to the...
5.
Lopez-Tello J, Yong H, Sandovici I, Dowsett G, Christoforou E, Salazar-Petres E, et al.
Cell Metab . 2023 Jul; 35(7):1195-1208.e6. PMID: 37437545
Maternal-offspring interactions in mammals involve both cooperation and conflict. The fetus has evolved ways to manipulate maternal physiology to enhance placental nutrient transfer, but the mechanisms involved remain unclear. The...
6.
Salazar-Petres E, Pereira-Carvalho D, Lopez-Tello J, Sferruzzi-Perri A
Cells . 2023 Mar; 12(5). PMID: 36899933
Adverse maternal environments such as small size, malnutrition, and metabolic conditions are known to influence fetal growth outcomes. Similarly, fetal growth and metabolic alterations may alter the intrauterine environment and...
7.
Lopez-Tello J, Sferruzzi-Perri A
Front Endocrinol (Lausanne) . 2023 Feb; 14:1116770. PMID: 36843585
Conditions such as small for gestational age (SGA), which is defined as birthweight less than 10 percentile for gestational age can predispose to neurodevelopmental abnormalities compared to babies with normal...
8.
Sferruzzi-Perri A, Lopez-Tello J, Salazar-Petres E
Exp Physiol . 2022 Dec; 108(3):371-397. PMID: 36484327
New Findings: What is the topic of this review? How the placenta, which transports nutrients and oxygen to the fetus, may alter its support of fetal growth developmentally and with...
9.
Pereira-Carvalho D, Salazar-Petres E, Lopez-Tello J, Sferruzzi-Perri A
Vet Sci . 2022 Sep; 9(9). PMID: 36136716
Fetal growth is reliant on placental formation and function, which, in turn, requires the energy produced by the mitochondria. Prior work has shown that both mother and fetus operate via...
10.
Lopez-Tello J, Salazar-Petres E, Webb L, Fowden A, Sferruzzi-Perri A
Front Cell Dev Biol . 2022 Jul; 10:928210. PMID: 35846351
Pregnancy requires adaptations in maternal metabolism to support fetal growth. The phosphoinositol-3-kinase (PI3K) signalling pathway controls multiple biological processes and defects in this pathway are linked to metabolic disorders including...