Jorge G Ferreira
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Explore the profile of Jorge G Ferreira including associated specialties, affiliations and a list of published articles.
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17
Citations
217
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Recent Articles
1.
Dantas M, Vareiro D, Ferreira J
Bio Protoc
. 2024 Jun;
14(6):e4959.
PMID: 38841288
Proliferating cells need to cope with extensive cytoskeletal and nuclear remodeling as they prepare to divide. These events are tightly regulated by the nuclear translocation of the cyclin B1-CDK1 complex,...
2.
Lima J, Ferreira J
Nucleus
. 2024 Mar;
15(1):2330947.
PMID: 38533923
Cellular behavior is continuously influenced by mechanical forces. These forces span the cytoskeleton and reach the nucleus, where they trigger mechanotransduction pathways that regulate downstream biochemical events. Therefore, the nucleus...
3.
Lima J, Pereira A, Ferreira J
Life Sci Alliance
. 2024 Jan;
7(4).
PMID: 38228373
Accurate centrosome separation and positioning during early mitosis relies on force-generating mechanisms regulated by a combination of extracellular, cytoplasmic, and nuclear cues. The identity of the nuclear cues involved in...
4.
Dantas M, Oliveira A, Aguiar P, Maiato H, Ferreira J
J Cell Biol
. 2022 Oct;
221(12).
PMID: 36222828
As cells prepare to divide, they must ensure that enough space is available to assemble the mitotic machinery without perturbing tissue homeostasis. To do so, cells undergo a series of...
5.
Nunes V, Dantas M, Lima J, Ferreira J
Methods Mol Biol
. 2021 Jun;
2329:179-194.
PMID: 34085223
Cell division requires a dynamic reorganization of cytoskeletal and nuclear components. One essential step is the separation of centrosomes, which allows the assembly of a microtubule-based mitotic spindle. This has...
6.
Dantas M, Lima J, Ferreira J
Front Cell Dev Biol
. 2021 Apr;
9:649899.
PMID: 33816500
In preparation for mitosis, cells undergo extensive reorganization of the cytoskeleton and nucleus, so that chromosomes can be efficiently segregated into two daughter cells. Coordination of these cytoskeletal and nuclear...
7.
Nunes V, Ferreira J
Semin Cell Dev Biol
. 2021 Mar;
117:42-51.
PMID: 33726956
Accurate chromosome segregation requires a complete restructuring of cellular organization. Microtubules remodel to assemble a mitotic spindle and the actin cytoskeleton rearranges to form a stiff actomyosin cortex. These cytoplasmic...
8.
Castro D, Nunes V, Lima J, Ferreira J, Aguiar P
J Cell Sci
. 2020 Nov;
133(24).
PMID: 33199521
During the initial stages of mitosis, multiple mechanisms drive centrosome separation and positioning. How they are coordinated to promote centrosome migration to opposite sides of the nucleus remains unclear. Here,...
9.
Nunes V, Dantas M, Castro D, Vitiello E, Wang I, Carpi N, et al.
Mol Biol Cell
. 2020 Apr;
31(16):1675-1690.
PMID: 32348198
During the initial stages of cell division, the cytoskeleton is extensively reorganized so that a bipolar mitotic spindle can be correctly assembled. This process occurs through the action of molecular...
10.
Ferreira L, Orr B, Rajendraprasad G, Pereira A, Lemos C, Lima J, et al.
J Cell Biol
. 2020 Apr;
219(4).
PMID: 32328631
Incorrect kinetochore-microtubule attachments during mitosis can lead to chromosomal instability, a hallmark of human cancers. Mitotic error correction relies on the kinesin-13 MCAK, a microtubule depolymerase whose activity in vitro...