Jorge Dorado
Overview
Explore the profile of Jorge Dorado including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
8
Citations
409
Followers
0
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Recent Articles
1.
Lopez-Gil J, Garcia-Silva S, Ruiz-Canas L, Navarro D, Palencia-Campos A, Giraldez-Trujillo A, et al.
Gut
. 2024 May;
73(9):1489-1508.
PMID: 38754953
Objective: Pancreatic ductal adenocarcinoma (PDAC) has limited therapeutic options, particularly with immune checkpoint inhibitors. Highly chemoresistant 'stem-like' cells, known as cancer stem cells (CSCs), are implicated in PDAC aggressiveness. Thus,...
2.
Cioffi M, Trabulo S, Sanchez-Ripoll Y, Miranda-Lorenzo I, Lonardo E, Dorado J, et al.
Gut
. 2015 Apr;
64(12):1936-48.
PMID: 25887381
Objective: Cancer stem cells (CSCs) represent the root of many solid cancers including pancreatic ductal adenocarcinoma, are highly chemoresistant and represent the cellular source for disease relapse. However the mechanisms...
3.
Miranda-Lorenzo I, Dorado J, Lonardo E, Alcala S, Serrano A, Clausell-Tormos J, et al.
Nat Methods
. 2014 Sep;
11(11):1161-9.
PMID: 25262208
Cancer stem cells (CSCs) are thought to drive tumor growth, metastasis and chemoresistance. Although surface markers such as CD133 and CD44 have been successfully used to isolate CSCs, their expression...
4.
Lonardo E, Cioffi M, Sancho P, Sanchez-Ripoll Y, Trabulo S, Dorado J, et al.
PLoS One
. 2013 Nov;
8(10):e76518.
PMID: 24204632
Pancreatic ductal adenocarcinomas contain a subset of exclusively tumorigenic cancer stem cells (CSCs), which are capable of repopulating the entire heterogeneous cancer cell populations and are highly resistant to standard...
5.
Balic A, Dorado J, Alonso-Gomez M, Heeschen C
Exp Cell Res
. 2011 Nov;
318(6):691-704.
PMID: 22119145
Emerging evidence suggests that stem cells play a crucial role not only in the generation and maintenance of different tissues, but also in the development and progression of malignancies. For...
6.
Cioffi M, Dorado J, Baeuerle P, Heeschen C
Clin Cancer Res
. 2011 Nov;
18(2):465-74.
PMID: 22096026
Purpose: Tumor-initiating cells with stem-like properties, also termed cancer stem cells (CSC), have been shown to sustain tumor growth as well as metastasis and are highly resistant to chemotherapy. Because...
7.
Dorado J, Lonardo E, Miranda-Lorenzo I, Heeschen C
J Gastroenterol
. 2011 Jun;
46(8):966-73.
PMID: 21698355
Since the identification of self-renewing cells in the hematopoietic system several decades ago, stem cells have changed the way we study biology and medicine. Solid tumors contain a distinct subpopulation...
8.
Cocca C, Dorado J, Calvo E, Lopez J, Santos A, Perez-Castillo A
Biochem Pharmacol
. 2009 Jul;
78(10):1330-9.
PMID: 19576185
15-Deoxi-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)) is known to play an important role in the pathophysiology of carcinogenesis, however, the molecular mechanisms underlying these effects are not yet fully understood. Recently, we have...