Jorge A Benitez
Overview
Explore the profile of Jorge A Benitez including associated specialties, affiliations and a list of published articles.
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Articles
53
Citations
1227
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Recent Articles
1.
Ledderose J, Benitez J, Roberts A, Reed R, Bintig W, Larkum M, et al.
Brain
. 2022 May;
145(10):3608-3621.
PMID: 35603900
The lipid phosphatase PTEN (phosphatase and tensin homologue on chromosome 10) is a key tumour suppressor gene and an important regulator of neuronal signalling. PTEN mutations have been identified in...
2.
Benitez J, Finlay D, Castanza A, Parisian A, Ma J, Longobardi C, et al.
Neuro Oncol
. 2021 Jan;
23(7):1072-1086.
PMID: 33428749
Background: Glioblastoma (GBM) is the most common primary brain tumor in adults with a median survival of approximately 15 months; therefore, more effective treatment options for GBM are required. To...
3.
Koga T, Chaim I, Benitez J, Markmiller S, Parisian A, Hevner R, et al.
Nat Commun
. 2020 Apr;
11(1):1958.
PMID: 32312984
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
4.
Koga T, Chaim I, Benitez J, Markmiller S, Parisian A, Hevner R, et al.
Nat Commun
. 2020 Jan;
11(1):550.
PMID: 31992716
Many cellular models aimed at elucidating cancer biology do not recapitulate pathobiology including tumor heterogeneity, an inherent feature of cancer that underlies treatment resistance. Here we introduce a cancer modeling...
5.
Ma J, Benitez J, Li J, Miki S, Ponte de Albuquerque C, Galatro T, et al.
Cancer Cell
. 2019 Dec;
36(6):690-691.
PMID: 31821785
No abstract available.
6.
Ayala J, Benitez J, Silva A
J Microbiol Methods
. 2019 Aug;
165:105702.
PMID: 31454505
We describe a proteomic approach to identify transcription factors binding to a target promoter. The method's usefulness was tested by identifying proteins binding to the Vibrio cholerae rpoS promoter in...
7.
Ma J, Benitez J, Li J, Miki S, Ponte de Albuquerque C, Galatro T, et al.
Cancer Cell
. 2019 May;
35(5):816.
PMID: 31085179
No abstract available.
8.
Ma J, Benitez J, Li J, Miki S, Ponte de Albuquerque C, Galatro T, et al.
Cancer Cell
. 2019 Mar;
35(3):504-518.e7.
PMID: 30827889
Ionizing radiation (IR) and chemotherapy are standard-of-care treatments for glioblastoma (GBM) patients and both result in DNA damage, however, the clinical efficacy is limited due to therapeutic resistance. We identified...
9.
Ayala J, Benitez J, Silva A
Methods Mol Biol
. 2018 Jul;
1839:65-75.
PMID: 30047055
Chromatin immunoprecipitation (ChIP) measures the physical association between a protein and DNA in the cell. In combination with next-generation sequencing, the technique enables the identification of DNA targets for the...
10.
Yu O, Benitez J, Plouffe S, Ryback D, Klein A, Smith J, et al.
Oncogene
. 2018 Jun;
37(41):5492-5507.
PMID: 29887596
The role of YAP (Yes-associated protein 1) and MRTF-A (myocardin-related transcription factor A), two transcriptional co-activators regulated downstream of GPCRs (G protein-coupled receptors) and RhoA, in the growth of glioblastoma...