Jordan Jacobelli
Overview
Explore the profile of Jordan Jacobelli including associated specialties, affiliations and a list of published articles.
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44
Citations
1509
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Recent Articles
1.
Abdelazeem K, Nguyen D, Corbo S, Darragh L, Matsumoto M, Van Court B, et al.
Oncogene
. 2024 Nov;
44(3):130-146.
PMID: 39489818
The EphB4-ephrinB2 signaling axis has been heavily implicated in metastasis across numerous cancer types. Our emerging understanding of the dichotomous roles that EphB4 and ephrinB2 play in head and neck...
2.
Sigler A, Thompson S, Ellwood-Digel L, Kandasamy A, Michaels M, Thumkeo D, et al.
Front Immunol
. 2024 Oct;
15:1467415.
PMID: 39430739
Lymphocyte trafficking and migration through tissues is critical for adaptive immune function and, to perform their roles, T cells must be able to navigate through diverse tissue environments that present...
3.
Abdelazeem K, Nguyen D, Corbo S, Darragh L, Matsumoto M, Van Court B, et al.
bioRxiv
. 2024 Aug;
PMID: 39091728
The EphB4-ephrinB2 signaling axis has been heavily implicated in metastasis across numerous cancer types. Our emerging understanding of the dichotomous roles that EphB4 and ephrinB2 play in head and neck...
4.
Pierce S, Jacobelli J, Given K, Macklin W, Gopinath J, Siemens M, et al.
Neurophotonics
. 2024 Jun;
11(3):034311.
PMID: 38867758
Significance: Stimulated emission depletion (STED) is a powerful super-resolution microscopy technique that can be used for imaging live cells. However, the high STED laser powers can cause significant photobleaching and...
5.
Haist K, Gibbings S, Jacobelli J, Mould K, Henson P, Bratton D
iScience
. 2024 Apr;
27(4):109589.
PMID: 38623335
Sterile pyogranulomas and heightened cytokine production are hyperinflammatory hallmarks of Chronic Granulomatous Disease (CGD). Using peritoneal cells of zymosan-treated CGD (gp91) versus wild-type (WT) mice, an system of pyogranuloma formation...
6.
Waldman M, Rahkola J, Sigler A, Chung J, Willett B, Kedl R, et al.
Front Immunol
. 2022 Jun;
13:856977.
PMID: 35757762
Naïve T cell activation in secondary lymphoid organs such as lymph nodes (LNs) occurs upon recognition of cognate antigen presented by antigen presenting cells (APCs). T cell activation requires cytoskeleton...
7.
Kremer K, Buser A, Thumkeo D, Narumiya S, Jacobelli J, Pelanda R, et al.
Proc Natl Acad Sci U S A
. 2022 Apr;
119(15):e2118816119.
PMID: 35394866
Cancer and chronic infections often increase levels of the bioactive lipid, lysophosphatidic acid (LPA), that we have demonstrated acts as an inhibitory ligand upon binding LPAR5 on CD8 T cells,...
8.
Jacobelli J, Buser A, Heiden D, Friedman R
Immunol Rev
. 2021 Nov;
306(1):181-199.
PMID: 34825390
Autoimmunity arises when mechanisms of immune tolerance fail. Here we discuss mechanisms of T cell activation and tolerance and the dynamics of the autoimmune response at the site of disease....
9.
Lindsay R, Whitesell J, Dew K, Rodriguez E, Sandor A, Tracy D, et al.
J Exp Med
. 2021 Aug;
218(10).
PMID: 34415994
Understanding mechanisms of immune regulation is key to developing immunotherapies for autoimmunity and cancer. We examined the role of mononuclear phagocytes during peripheral T cell regulation in type 1 diabetes...
10.
Thompson S, Waldman M, Jacobelli J
FEBS J
. 2021 Jul;
289(20):6154-6171.
PMID: 34273243
During their life span, T cells are tasked with patrolling the body for potential pathogens. To do so, T cells migrate through numerous distinct anatomical sites and tissue environments with...