Jordan A Kreidberg
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Explore the profile of Jordan A Kreidberg including associated specialties, affiliations and a list of published articles.
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51
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2191
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Recent Articles
11.
Qin S, Taglienti M, Cai L, Zhou J, Kreidberg J
J Am Soc Nephrol
. 2012 Jun;
23(8):1309-18.
PMID: 22677559
The mechanisms of cystogenesis in autosomal dominant polycystic kidney disease (ADPKD) are not fully understood. Hyperactivation of the tyrosine kinase c-Met contributes to cyst formation, but we do not know...
12.
Ho J, Kreidberg J
Pediatr Nephrol
. 2012 Jun;
28(2):219-25.
PMID: 22660936
The discovery of microRNAs (miRNAs) as novel regulators of gene expression has led to a marked change in how gene regulation is viewed, with important implications for development and disease....
13.
Ho J, Kreidberg J
J Am Soc Nephrol
. 2012 Feb;
23(3):400-4.
PMID: 22302196
MicroRNAs (miRNAs) are a group of small, noncoding RNAs that act as novel regulators of gene expression through the post-transcriptional repression of their target mRNAs. miRNAs have been implicated in...
14.
Schumacher V, Schlotzer-Schrehardt U, Karumanchi S, Shi X, Zaia J, Jeruschke S, et al.
J Am Soc Nephrol
. 2011 Jul;
22(7):1286-96.
PMID: 21719793
Paracrine signaling between podocytes and glomerular endothelial cells through vascular endothelial growth factor A (VEGFA) maintains a functional glomerular filtration barrier. Heparan sulfate proteoglycans (HSPGs), located on the cell surface...
15.
Ho J, Pandey P, Schatton T, Sims-Lucas S, Khalid M, Frank M, et al.
J Am Soc Nephrol
. 2011 May;
22(6):1053-63.
PMID: 21546576
Understanding the mechanisms that regulate nephron progenitors during kidney development should aid development of therapies for renal failure. MicroRNAs, which modulate gene expression through post-transcriptional repression of specific target mRNAs,...
16.
Pandey P, Qin S, Ho J, Zhou J, Kreidberg J
BMC Syst Biol
. 2011 Apr;
5:56.
PMID: 21518438
Background: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by cyst formation throughout the kidney parenchyma. It is caused by mutations in either of two genes, PKD1 and PKD2. Mice...
17.
Jarad G, Pippin J, Shankland S, Kreidberg J, Miner J
Am J Physiol Renal Physiol
. 2011 Jan;
300(3):F811-20.
PMID: 21209007
Dystroglycan (DG or DAG1) is considered a critical link between the basement membrane and the cytoskeleton in multiple tissues. DG consists of two subunits, an extracellular α-subunit that binds laminin...
18.
Kreidberg J
Organogenesis
. 2010 Oct;
6(2):61-70.
PMID: 20885852
Kidney development has been studied over the past sixty years as a model of embryonic induction during organogenesis. Wilms' tumor-1 (WT1), that encodes a transcription factor and RNA-binding protein, was...
19.
Langsdorf A, Schumacher V, Shi X, Tran T, Zaia J, Jain S, et al.
Glycobiology
. 2010 Sep;
21(2):152-61.
PMID: 20855470
Glial cell line-derived neurotrophic factor (GDNF) is a heparan sulfate (HS)-binding factor. GDNF is produced by somatic Sertoli cells, where it signals to maintain spermatogonial stem cells (SSCs) and reproduction....
20.
Qin S, Taglienti M, Nauli S, Contrino L, Takakura A, Zhou J, et al.
J Clin Invest
. 2010 Sep;
120(10):3617-28.
PMID: 20852388
Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited disorder that is caused by mutations at two loci, polycystin 1 (PKD1) and polycystin 2 (PKD2). It is characterized by...