Jongkyeong Chung
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Explore the profile of Jongkyeong Chung including associated specialties, affiliations and a list of published articles.
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89
Citations
5178
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Recent Articles
11.
Nishida H, Okada M, Yang L, Takano T, Tabata S, Soga T, et al.
Elife
. 2021 Apr;
10.
PMID: 33902813
Oncogenes often promote cell death as well as proliferation. How oncogenes drive these diametrically opposed phenomena remains to be solved. A key question is whether cell death occurs as a...
12.
Choi S, Song B, Shin H, Won C, Kim T, Yoshida H, et al.
Genes Genomics
. 2021 Apr;
43(7):737-748.
PMID: 33864616
Background: Haploinsufficiency of the human nuclear receptor binding suppressor of variegation 3-9, enhancer of zeste, and trithorax (SET) domain 1 (NSD1) gene causes a developmental disorder called Sotos syndrome 1...
13.
Park J, Jun K, Choi Y, Yoon E, Kim W, Jang Y, et al.
J Biol Chem
. 2020 Nov;
296:100040.
PMID: 33162394
The Hippo pathway controls organ size and tissue homeostasis through the regulation of cell proliferation and apoptosis. However, the exact molecular mechanisms underpinning Hippo pathway regulation are not fully understood....
14.
Jang Y, Choi Y, Jun K, Chung J
Mol Cells
. 2020 Aug;
43(8):705-717.
PMID: 32759469
While the growth factors like insulin initiate a signaling cascade to induce conformational changes in the mechanistic target of rapamycin complex 1 (mTORC1), amino acids cause the complex to localize...
15.
Ham S, Lee D, Yoo H, Jun K, Shin H, Chung J
Proc Natl Acad Sci U S A
. 2020 Feb;
117(8):4281-4291.
PMID: 32047033
VDAC1 is a critical substrate of Parkin responsible for the regulation of mitophagy and apoptosis. Here, we demonstrate that VDAC1 can be either mono- or polyubiquitinated by Parkin in a...
16.
Hwang S, Bang S, Kim W, Chung J
J Biol Chem
. 2020 Jan;
295(8):2336-2347.
PMID: 31959630
Cell growth is positively controlled by the phosphoinositide 3-kinase (PI3K)-target of rapamycin (TOR) signaling pathway under conditions of abundant growth factors and nutrients. To discover additional mechanisms that regulate cell...
17.
Ly L, Ly D, Nguyen N, Kim J, Yoo H, Chung J, et al.
Mol Cells
. 2020 Jan;
43(1):66-75.
PMID: 31931552
Saturated fatty acids contribute to β-cell dysfunction in the onset of type 2 diabetes mellitus. Cellular responses to lipotoxicity include oxidative stress, endoplasmic reticulum (ER) stress, and blockage of autophagy....
18.
Vila I, Park M, Setijono S, Yao Y, Kim H, Badin P, et al.
JCI Insight
. 2019 Jul;
4(13).
PMID: 31292296
Ubiquitin-conjugating enzyme E2O (UBE2O) is expressed preferentially in metabolic tissues, but its role in regulating energy homeostasis has yet to be defined. Here we find that UBE2O is markedly upregulated...
19.
Yoon W, Hwang S, Lee S, Chung J
PLoS Genet
. 2019 May;
15(5):e1008184.
PMID: 31125351
The function of AarF domain-containing kinase 1 (ADCK1) has not been thoroughly revealed. Here we identified that ADCK1 utilizes YME1-like 1 ATPase (YME1L1) to control optic atrophy 1 (OPA1) and...
20.
Kim Y, Um J, Yoon J, Kim H, Lee D, Lee Y, et al.
FASEB J
. 2019 May;
33(9):9742-9751.
PMID: 31120803
Mitophagy has been implicated in mitochondrial quality control and in various human diseases. However, the study of mitophagy remains limited. We previously explored mitophagy using a transgenic mouse expressing the...