Jones G Parker
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Explore the profile of Jones G Parker including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
1077
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Recent Articles
1.
Yun S, Parker J
Synapse
. 2025 Feb;
79(2):e70011.
PMID: 40013455
Genetically encoded fluorescent sensors of neural activity have become a mainstay of basic neuroscience. However, preclinical drug development has been slower to adopt these tools. Recently, we used miniature microscopes...
2.
Borkar C, Stelly C, Fu X, Dorofeikova M, Le Q, Vutukuri R, et al.
Nature
. 2024 Jan;
625(7996):743-749.
PMID: 38233522
Survival requires the selection of appropriate behaviour in response to threats, and dysregulated defensive reactions are associated with psychiatric illnesses such as post-traumatic stress and panic disorder. Threat-induced behaviours, including...
3.
Lorch C, Hayes N, Xia J, Fleps S, McMorrow H, Province H, et al.
Cell Rep
. 2024 Jan;
43(2):113675.
PMID: 38224492
Rapid gut-brain communication is critical to maintain energy balance and is disrupted in diet-induced obesity. In particular, the role of carbohydrate overconsumption in the regulation of interoceptive circuits in vivo...
4.
Yun S, Yang B, Anair J, Martin M, Fleps S, Pamukcu A, et al.
Nat Neurosci
. 2023 Jul;
26(8):1417-1428.
PMID: 37443282
Elevated dopamine transmission in psychosis is assumed to unbalance striatal output through D1- and D2-receptor-expressing spiny-projection neurons (SPNs). Antipsychotic drugs are thought to re-balance this output by blocking D2 receptors...
5.
Moya N, Yun S, Fleps S, Martin M, Nadel J, Beutler L, et al.
Neuropsychopharmacology
. 2022 Nov;
48(4):690-699.
PMID: 36380221
Excess dopamine release in the dorsal striatum (DS) is linked to psychosis. Antipsychotics are thought to work by blocking striatal D2 dopamine receptors, but they lack efficacy for the negative...
6.
Legaria A, Matikainen-Ankney B, Yang B, Ahanonu B, Licholai J, Parker J, et al.
Nat Neurosci
. 2022 Aug;
25(9):1124-1128.
PMID: 36042311
Fiber photometry enables recording of population neuronal calcium dynamics in awake mice. While the popularity of fiber photometry has grown in recent years, it remains unclear whether photometry reflects changes...
7.
Trevathan J, Asp A, Nicolai E, Trevathan J, Kremer N, Kozai T, et al.
J Neural Eng
. 2020 Sep;
PMID: 32916665
After decades of study in humans and animal models, there remains a lack of consensus regarding how the action of electrical stimulation on neuronal and non-neuronal elements - e.g. neuropil,...
8.
Parker J, Marshall J, Ahanonu B, Wu Y, Kim T, Grewe B, et al.
Nature
. 2018 May;
557(7704):177-182.
PMID: 29720658
Loss of dopamine in Parkinson's disease is hypothesized to impede movement by inducing hypo- and hyperactivity in striatal spiny projection neurons (SPNs) of the direct (dSPNs) and indirect (iSPNs) pathways...
9.
Grewe B, Grundemann J, Kitch L, Lecoq J, Parker J, Marshall J, et al.
Nature
. 2017 Mar;
543(7647):670-675.
PMID: 28329757
The brain's ability to associate different stimuli is vital for long-term memory, but how neural ensembles encode associative memories is unknown. Here we studied how cell ensembles in the basal...
10.
Hamel E, Grewe B, Parker J, Schnitzer M
Neuron
. 2015 Apr;
86(1):140-59.
PMID: 25856491
Fluorescence imaging offers expanding capabilities for recording neural dynamics in behaving mammals, including the means to monitor hundreds of cells targeted by genetic type or connectivity, track cells over weeks,...