Jonathan R Bostrom
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Explore the profile of Jonathan R Bostrom including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
144
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Recent Articles
1.
Durazo-Martinez K, Chaudhari J, Sherry L, Webster D, Martins K, Bostrom J, et al.
Vet Microbiol
. 2025 Mar;
304:110450.
PMID: 40073612
CD163 is the primary receptor for PRRSV, and its SRCR5 domain, encoded by exon 7, is crucial for supporting PRRSV infection. Previous studies have used CRISPR/Cas9 technology to remove exon...
2.
Rowland R, Salgado B, Lowe J, Sonstegard T, Carlson D, Martins K, et al.
Vet Microbiol
. 2024 Sep;
298:110255.
PMID: 39332164
Following infection of a porcine dam with PRRSV around 90 days of gestation, the virus crosses the placenta and starts to infect fetuses. This can lead to consequences such as...
3.
Cuellar C, Amaral T, Rodriguez-Villamil P, Ongaratto F, Martinez D, Labrecque R, et al.
FASEB Bioadv
. 2024 Aug;
6(8):223-234.
PMID: 39114445
Global warming is a major challenge to the sustainable and humane production of food because of the increased risk of livestock to heat stress. Here, the example of the prolactin...
4.
Salgado B, Rivas R, Pinto D, Sonstegard T, Carlson D, Martins K, et al.
Antiviral Res
. 2024 Jan;
221:105793.
PMID: 38184111
CD163 expressed on cell surface of porcine alveolar macrophages (PAMs) serves as a cellular entry receptor for porcine reproductive and respiratory syndrome virus (PRRSV). The extracellular portion of CD163 contains...
5.
Workman A, Heaton M, Vander Ley B, Webster D, Sherry L, Bostrom J, et al.
PNAS Nexus
. 2023 May;
2(5):pgad125.
PMID: 37181049
Bovine viral diarrhea virus (BVDV) is one of the most important viruses affecting the health and well-being of bovine species throughout the world. Here, we used CRISPR-mediated homology-directed repair and...
6.
Florez J, Martins K, Solin S, Bostrom J, Rodriguez-Villamil P, Ongaratto F, et al.
Front Genet
. 2023 Jan;
13:1078991.
PMID: 36685939
Most male pigs are surgically castrated to avoid puberty-derived boar taint and aggressiveness. However, this surgical intervention represents a welfare concern in swine production. Disrupting porcine is hypothesized to delay...
7.
Florez Murillo J, Landaeta-Hernandez A, Kim E, Bostrom J, Larson S, Perez OBrien A, et al.
Anim Genet
. 2020 Dec;
52(1):132-134.
PMID: 33259090
No abstract available.
8.
Flinn M, Otten C, Brandt Z, Bostrom J, Kenarsary A, Wan T, et al.
Development
. 2020 Aug;
147(16).
PMID: 32843528
The Hippo-Yap pathway regulates multiple cellular processes in response to mechanical and other stimuli. In , the polarity protein Lethal (2) giant larvae [L(2)gl], negatively regulates Hippo-mediated transcriptional output. However,...
9.
Brandt Z, Echert A, Bostrom J, North P, Link B
Development
. 2020 May;
147(12).
PMID: 32439761
The development of the biliary system is a complex yet poorly understood process, with relevance to multiple diseases, including biliary atresia, choledochal cysts and gallbladder agenesis. We present here a...
10.
Clark E, Nonarath H, Bostrom J, Link B
Dis Model Mech
. 2019 Dec;
13(1).
PMID: 31852729
Induction of endoplasmic reticulum (ER) stress is associated with diverse developmental and degenerative diseases. Modified ER homeostasis causes activation of conserved stress pathways at the ER called the unfolded protein...