Jonathan P Britt
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Explore the profile of Jonathan P Britt including associated specialties, affiliations and a list of published articles.
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24
Citations
1644
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Recent Articles
1.
Lax E, Do Carmo S, Enuka Y, Sapozhnikov D, Welikovitch L, Mahmood N, et al.
Transl Psychiatry
. 2023 Jul;
13(1):259.
PMID: 37443311
The Methyl-CpG-Binding Domain Protein family has been implicated in neurodevelopmental disorders. The Methyl-CpG-binding domain 2 (Mbd2) binds methylated DNA and was shown to play an important role in cancer and...
2.
Lafferty C, Christinck T, Britt J
Methods
. 2021 Jul;
203:46-55.
PMID: 34314828
Improvements in all-optical means of monitoring and manipulating neural activity have generated new ways of studying psychiatric disease. The combination of calcium imaging techniques with optogenetics to concurrently record and...
3.
De Gregorio D, Popic J, Enns J, Inserra A, Skalecka A, Markopoulos A, et al.
Proc Natl Acad Sci U S A
. 2021 Jan;
118(5).
PMID: 33495318
Clinical studies have reported that the psychedelic lysergic acid diethylamide (LSD) enhances empathy and social behavior (SB) in humans, but its mechanism of action remains elusive. Using a multidisciplinary approach...
4.
Lafferty C, Britt J
Front Neural Circuits
. 2020 Apr;
14:10.
PMID: 32269514
Archaerhodopsin (ArchT)-mediated photoinhibition of axon terminals is commonly used to test the involvement of specific long-range neural projections in behavior. Although sustained activation of this opsin in axon terminals has...
5.
Lafferty C, Yang A, Mendoza J, Britt J
Cell Rep
. 2020 Mar;
30(11):3729-3742.e3.
PMID: 32187545
The nucleus accumbens (NAc) contributes to behavioral inhibition and compulsions, but circuit mechanisms are unclear. Recent evidence suggests that amygdala and thalamic inputs exert opposing control over behavior, much like...
6.
Lafferty C, Britt J
Biol Psychiatry
. 2020 Mar;
87(7):592-594.
PMID: 32164914
No abstract available.
7.
Yang A, Mendoza J, Lafferty C, Lacroix F, Britt J
Biol Psychiatry
. 2019 Nov;
87(7):597-608.
PMID: 31699294
Background: Insight into the neural basis of hedonic processing has come from studies of food palatability in rodents. Pharmacological manipulations of the nucleus accumbens shell (NAcSh) have repeatedly been demonstrated ...
8.
Mendoza J, Lafferty C, Yang A, Britt J
Cell Rep
. 2019 Nov;
29(6):1429-1437.e3.
PMID: 31693885
Cue-evoked midbrain dopamine (DA) neuron activity reflects expected value, but its influence on reward assessment is unclear. In mice performing a trial-based operant task, we test if bidirectional manipulations of...
9.
Reed S, Lafferty C, Mendoza J, Yang A, Davidson T, Grosenick L, et al.
Neuron
. 2018 Aug;
99(6):1260-1273.e4.
PMID: 30146308
Reward-seeking behavior is regulated by a diverse collection of inputs to the nucleus accumbens (NAc). The information encoded in each excitatory afferent to the NAc is unknown, in part because...
10.
Quiroz C, Orru M, Rea W, Ciudad-Roberts A, Yepes G, Britt J, et al.
J Neurosci
. 2016 Jan;
36(3):851-9.
PMID: 26791215
It is generally assumed that infralimbic cortex (ILC) and prelimbic cortex, two adjacent areas of the medial prefrontal cortex (mPFC) in rodents, provide selective excitatory glutamatergic inputs to the nucleus...