Jonathan P Britt
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Explore the profile of Jonathan P Britt including associated specialties, affiliations and a list of published articles.
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24
Citations
1644
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Recent Articles
11.
Zhang S, Qi J, Li X, Wang H, Britt J, Hoffman A, et al.
Nat Neurosci
. 2015 Feb;
18(3):386-92.
PMID: 25664911
Mesoaccumbens fibers are thought to co-release dopamine and glutamate. However, the mechanism is unclear, and co-release by mesoaccumbens fibers has not been documented. Using electron microcopy, we found that some...
12.
McDevitt R, Tiran-Cappello A, Shen H, Balderas I, Britt J, Marino R, et al.
Cell Rep
. 2014 Sep;
8(6):1857-1869.
PMID: 25242321
The dorsal raphe nucleus (DRN) contains the largest group of serotonin-producing neurons in the brain and projects to regions controlling reward. Although pharmacological studies suggest that serotonin inhibits reward seeking,...
13.
McDevitt R, Reed S, Britt J
Neuropsychiatr Dis Treat
. 2014 Aug;
10:1369-79.
PMID: 25092982
There have been significant advances in the treatment of psychiatric disease in the last half century, but it is still unclear which neural circuits are ultimately responsible for specific disease...
14.
Jayanthi S, McCoy M, Chen B, Britt J, Kourrich S, Yau H, et al.
Biol Psychiatry
. 2013 Nov;
76(1):47-56.
PMID: 24239129
Background: Chronic methamphetamine (METH) exposure causes neuroadaptations at glutamatergic synapses. Methods: To identify the METH-induced epigenetic underpinnings of these neuroadaptations, we injected increasing METH doses to rats for 2 weeks...
15.
Britt J, Bonci A
Neuron
. 2013 Aug;
79(3):406-7.
PMID: 23931990
Cigarette smokers tend to drink more alcohol than their nonsmoking peers. In this issue of Neuron, Doyon et al. (2013) found that nicotine-induced increases in stress hormones can augment ethanol...
16.
Britt J, Bonci A
Curr Opin Neurobiol
. 2013 Feb;
23(4):539-45.
PMID: 23375167
Exposure to addictive drugs can result in maladaptive alterations in neural circuit function. This review highlights recent progress made in identifying the organization, function, and cellular plasticity of the ventral...
17.
Britt J, Benaliouad F, McDevitt R, Stuber G, Wise R, Bonci A
Neuron
. 2012 Nov;
76(4):790-803.
PMID: 23177963
Excitatory afferents to the nucleus accumbens (NAc) are thought to facilitate reward seeking by encoding reward-associated cues. Selective activation of different glutamatergic inputs to the NAc can produce divergent physiological...
18.
Britt J, McDevitt R, Bonci A
Curr Protoc Neurosci
. 2012 Oct;
Chapter 2:Unit2.16.
PMID: 23042500
Optogenetics-the use of optically activated proteins to control cell function-allows for control of neurons with an unprecedented degree of spatial, temporal, and neurochemical precision. Three protocols are presented in this...
19.
Stuber G, Britt J, Bonci A
Biol Psychiatry
. 2011 Dec;
71(12):1061-7.
PMID: 22196983
The manifestation of complex neuropsychiatric disorders, such as drug and alcohol addiction, is thought to result from progressive maladaptive alterations in neural circuit function. Clearly, repeated drug exposure alters a...
20.
Ding Y, Won L, Britt J, Lim S, McGehee D, Kang U
Proc Natl Acad Sci U S A
. 2010 Dec;
108(2):840-5.
PMID: 21187382
Treatment of Parkinson disease (PD) with L-3,4-dihydroxyphenylalanine (L-DOPA) dramatically relieves associated motor deficits, but L-DOPA-induced dyskinesias (LID) limit the therapeutic benefit over time. Previous investigations have noted changes in striatal...