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Jonathan P Belman

Explore the profile of Jonathan P Belman including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 251
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Recent Articles
1.
Chow R, Velu P, Deihimi S, Belman J, Youn A, Shah N, et al.
Blood Adv . 2025 Feb; PMID: 39938015
Mutations found in AML such as DNMT3A, TET2 and ASXL1 can be found in the peripheral blood of healthy adults - a phenomenon termed clonal hematopoiesis (CH). These mutations are...
2.
Le Coz C, Oldridge D, Herati R, De Luna N, Garifallou J, Cruz Cabrera E, et al.
Sci Immunol . 2023 Apr; 8(82):eade8162. PMID: 37027481
The mechanisms by which FOXP3 T follicular regulatory (Tfr) cells simultaneously steer antibody formation toward microbe or vaccine recognition and away from self-reactivity remain incompletely understood. To explore underappreciated heterogeneity...
3.
Belman J, Meng W, Wang H, Li J, Strauser H, Rosenfeld A, et al.
Cold Spring Harb Mol Case Stud . 2019 Nov; 6(1). PMID: 31776129
Transformation of follicular lymphoma (FL) into B-lymphoblastic leukemia/lymphoma (B-ALL/LBL) is rare and results in greatly increased aggressiveness of clinical course. Here we present extensive molecular analysis of this unusual transformation,...
4.
Habtemichael E, Alcazar-Roman A, Rubin B, Grossi L, Belman J, Julca O, et al.
J Biol Chem . 2015 May; 290(23):14454-61. PMID: 25944897
In adipose and muscle cells, insulin stimulates the exocytic translocation of vesicles containing GLUT4, a glucose transporter, and insulin-regulated aminopeptidase (IRAP), a transmembrane aminopeptidase. A substrate of IRAP is vasopressin,...
5.
Belman J, Bian R, Habtemichael E, Li D, Jurczak M, Alcazar-Roman A, et al.
J Biol Chem . 2015 Jan; 290(7):4447-63. PMID: 25561724
Insulin causes the exocytic translocation of GLUT4 glucose transporters to stimulate glucose uptake in fat and muscle. Previous results support a model in which TUG traps GLUT4 in intracellular, insulin-responsive...
6.
Belman J, Habtemichael E, Bogan J
Rev Endocr Metab Disord . 2013 Oct; 15(1):55-66. PMID: 24114239
Insulin regulates glucose uptake by controlling the subcellular location of GLUT4 glucose transporters. GLUT4 is sequestered within fat and muscle cells during low-insulin states, and is translocated to the cell...
7.
Jimenez-Gomez Y, Mattison J, Pearson K, Martin-Montalvo A, Palacios H, Sossong A, et al.
Cell Metab . 2013 Oct; 18(4):533-45. PMID: 24093677
Obesity is associated with a chronic, low-grade, systemic inflammation that may contribute to the development of insulin resistance and type 2 diabetes. Resveratrol, a natural compound with anti-inflammatory properties, is...
8.
Loffler M, Birkenfeld A, Philbrick K, Belman J, Habtemichael E, Booth C, et al.
J Biol Chem . 2013 Jun; 288(28):20135-50. PMID: 23744065
Insulin stimulates glucose uptake in 3T3-L1 adipocytes in part by causing endoproteolytic cleavage of TUG (tether containing a ubiquitin regulatory X (UBX) domain for glucose transporter 4 (GLUT4)). Cleavage liberates...
9.
Bogan J, Rubin B, Yu C, Loffler M, Orme C, Belman J, et al.
J Biol Chem . 2012 May; 287(28):23932-47. PMID: 22610098
To promote glucose uptake into fat and muscle cells, insulin causes the translocation of GLUT4 glucose transporters from intracellular vesicles to the cell surface. Previous data support a model in...