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Jonathan Mount

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Articles 6
Citations 24
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Recent Articles
1.
Lee S, Gao J, Thompson E, Mount J, Nichols C
J Biol Chem . 2025 Mar; :108393. PMID: 40074079
Inward rectifier Kir4.1 potassium channels are abundantly expressed in cells that are important for electrolyte homeostasis. Dysregulation of Kir4.1 underlies various neurological disorders. Here, through biochemical and structural studies of...
2.
He Z, Tu Y, Tsai C, Mount J, Zhang J, Tsai M, et al.
Nat Struct Mol Biol . 2024 Nov; PMID: 39609651
The human mitochondrial RNA splicing 2 protein (MRS2) has been implicated in Mg transport across mitochondrial inner membranes, thus having an important role in Mg homeostasis critical for mitochondrial integrity...
3.
Burtscher V, Mount J, Huang J, Cowgill J, Chang Y, Bickel K, et al.
Nat Commun . 2024 Jun; 15(1):5216. PMID: 38890331
Hyperpolarization and cyclic nucleotide (HCN) activated ion channels are critical for the automaticity of action potentials in pacemaking and rhythmic electrical circuits in the human body. Unlike most voltage-gated ion...
4.
He Z, Tu Y, Tsai C, Mount J, Zhang J, Tsai M, et al.
bioRxiv . 2023 Aug; PMID: 37645897
The human Mitochondrial RNA Splicing 2 protein (MRS2) has been implicated in Mg transport across mitochondrial inner membranes, thus playing an important role in Mg homeostasis critical for mitochondrial integrity...
5.
Burtscher V, Mount J, Cowgill J, Chang Y, Bickel K, Yuan P, et al.
bioRxiv . 2023 Aug; PMID: 37645882
Hyperpolarization and cyclic-nucleotide (HCN) activated ion channels play a critical role in generating self-propagating action potentials in pacemaking and rhythmic electrical circuits in the human body. Unlike most voltage-gated ion...
6.
Mount J, Maksaev G, Summers B, Fitzpatrick J, Yuan P
Nat Commun . 2022 Nov; 13(1):6904. PMID: 36371466
Mechanosensitive channels of small conductance, found in many living organisms, open under elevated membrane tension and thus play crucial roles in biological response to mechanical stress. Amongst these channels, MscK...
7.
Yakovenko O, Nunez J, Bensing B, Yu H, Mount J, Zeng J, et al.
Infect Immun . 2018 Mar; 86(6). PMID: 29581195
The binding of bacteria to platelets is thought to be a central event in the pathogenesis of infective endocarditis. The serine-rich repeat (SRR) glycoproteins of viridans group streptococci have been...