Jonathan H Badger
Overview
Explore the profile of Jonathan H Badger including associated specialties, affiliations and a list of published articles.
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57
Citations
6173
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Recent Articles
1.
Neoadjuvant vidutolimod and nivolumab in high-risk resectable melanoma: A prospective phase II trial
Davar D, Morrison R, Dzutsev A, Karunamurthy A, Chauvin J, Amatore F, et al.
Cancer Cell
. 2024 Nov;
42(11):1898-1918.e12.
PMID: 39486411
Intratumoral TLR9 agonists and anti-PD-1 produce clinical responses and broad immune activation. We conducted a single-arm study of neoadjuvant TLR9 agonist vidutolimod combined with anti-PD-1 nivolumab in high-risk resectable melanoma....
2.
Benedetti F, Mongodin E, Badger J, Munawwar A, Cellini A, Yuan W, et al.
J Transl Med
. 2024 Mar;
22(1):269.
PMID: 38475767
Background: Chemotherapy is a primary treatment for cancer, but its efficacy is often limited by cancer-associated bacteria (CAB) that impair tumor suppressor functions. Our previous research found that Mycoplasma fermentans...
3.
Soares N, Huguet-Tapia J, Guan D, Clark C, Yang K, Kluchka O, et al.
Appl Environ Microbiol
. 2023 Nov;
89(12):e0030823.
PMID: 38009923
While most plant-pathogenic species cause scab disease on a variety of plant hosts, is the sole causative agent of soil rot disease of sweet potato and closely related plant species....
4.
Badger J, Giordano R, Zimin A, Wappel R, Eskipehlivan S, Muller S, et al.
Curr Opin Insect Sci
. 2023 Nov;
61:101135.
PMID: 37926187
Insect symbionts can alter their host phenotype and their effects can range from beneficial to pathogenic. Moreover, many insects exhibit co-infections, making their study more challenging. Less than 1% of...
5.
McCulloch J, Davar D, Rodrigues R, Badger J, Fang J, Cole A, et al.
Nat Med
. 2022 Mar;
28(3):545-556.
PMID: 35228752
Ample evidence indicates that the gut microbiome is a tumor-extrinsic factor associated with antitumor response to anti-programmed cell death protein-1 (PD-1) therapy, but inconsistencies exist between published microbial signatures associated...
6.
Spencer C, McQuade J, Gopalakrishnan V, McCulloch J, Vetizou M, Cogdill A, et al.
Science
. 2021 Dec;
374(6575):1632-1640.
PMID: 34941392
Gut bacteria modulate the response to immune checkpoint blockade (ICB) treatment in cancer, but the effect of diet and supplements on this interaction is not well studied. We assessed fecal...
7.
Hild B, Dreier M, Oh J, McCulloch J, Badger J, Guo J, et al.
Nat Metab
. 2021 Aug;
3(8):1042-1057.
PMID: 34417593
Obesity and its consequences are among the greatest challenges in healthcare. The gut microbiome is recognized as a key factor in the pathogenesis of obesity. Using a mouse model, we...
8.
Davar D, Dzutsev A, McCulloch J, Rodrigues R, Chauvin J, Morrison R, et al.
Science
. 2021 Feb;
371(6529):595-602.
PMID: 33542131
Anti-programmed cell death protein 1 (PD-1) therapy provides long-term clinical benefits to patients with advanced melanoma. The composition of the gut microbiota correlates with anti-PD-1 efficacy in preclinical models and...
9.
Giordano R, Donthu R, Zimin A, Julca Chavez I, Gabaldon T, van Munster M, et al.
Insect Biochem Mol Biol
. 2020 Feb;
120:103334.
PMID: 32109587
The soybean aphid, Aphis glycines Matsumura (Hemiptera: Aphididae) is a serious pest of the soybean plant, Glycine max, a major world-wide agricultural crop. We assembled a de novo genome sequence...
10.
Kumar M, Singh P, Murugesan S, Vetizou M, McCulloch J, Badger J, et al.
Methods Mol Biol
. 2019 Sep;
2055:595-638.
PMID: 31502171
Humans are living ecosystems composed of human cells and microbes. The microbiome is the collection of microbes (microbiota) and their genes. Recent breakthroughs in the high-throughput sequencing technologies have made...