Jonathan D Stoltzfus
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Explore the profile of Jonathan D Stoltzfus including associated specialties, affiliations and a list of published articles.
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12
Citations
367
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Recent Articles
1.
Abdul Halim M, Rodriguez R, Stoltzfus J, Duggin I, Pohlschroder M
Mol Microbiol
. 2018 Feb;
108(3):276-287.
PMID: 29465796
Proper protein anchoring is key to the biogenesis of prokaryotic cell surfaces, dynamic, resilient structures that play crucial roles in various cell processes. A novel surface protein anchoring mechanism in...
2.
Lei W, Lok J, Yuan W, Zhang Y, Stoltzfus J, Gasser R, et al.
Sci Rep
. 2017 Aug;
7(1):8693.
PMID: 28821723
RIO kinases are essential atypical protein kinases in diverse prokaryotic and eukaryotic organisms, playing significant roles in yeast and humans. However, little is known about their functions in parasitic nematodes....
3.
Abdul Halim M, Stoltzfus J, Schulze S, Hippler M, Pohlschroder M
J Bacteriol
. 2017 Jan;
199(7).
PMID: 28069824
Most prokaryote-secreted proteins are transported to the cell surface using either the general secretion (Sec) or twin-arginine translocation (Tat) pathway. A majority of secreted proteins are anchored to the cell...
4.
Stoltzfus J, Pilgrim A, Herbert D
Mol Biochem Parasitol
. 2016 Nov;
215:11-22.
PMID: 27887974
The advent of high-throughput, next-generation sequencing methods combined with advances in computational biology and bioinformatics have greatly accelerated discovery within biomedical research. This "post-genomics" era has ushered in powerful approaches...
5.
Hunt V, Tsai I, Coghlan A, Reid A, Holroyd N, Foth B, et al.
Nat Genet
. 2016 Feb;
48(3):299-307.
PMID: 26829753
Soil-transmitted nematodes, including the Strongyloides genus, cause one of the most prevalent neglected tropical diseases. Here we compare the genomes of four Strongyloides species, including the human pathogen Strongyloides stercoralis,...
6.
Albarqi M, Stoltzfus J, Pilgrim A, Nolan T, Wang Z, Kliewer S, et al.
PLoS Pathog
. 2016 Jan;
12(1):e1005358.
PMID: 26727267
The complex life cycle of the parasitic nematode Strongyloides stercoralis leads to either developmental arrest of infectious third-stage larvae (iL3) or growth to reproductive adults. In the free-living nematode Caenorhabditis...
7.
Yuan W, Liu Y, Lok J, Stoltzfus J, Gasser R, Lei W, et al.
Parasit Vectors
. 2014 Dec;
7:561.
PMID: 25477034
Background: Right open reading frame protein kinase 3 (RIOK-3) belongs to the atypical kinase family. Unlike the other two members, RIOK-1 and RIOK-2, which are conserved from Archaea to humans,...
8.
Yuan W, Lok J, Stoltzfus J, Gasser R, Fang F, Lei W, et al.
PLoS Negl Trop Dis
. 2014 Aug;
8(8):e3062.
PMID: 25101874
Background: Some studies of Saccharomyces cerevisiae and mammals have shown that RIO protein kinases (RIOKs) are involved in ribosome biogenesis, cell cycle progression and development. However, there is a paucity...
9.
Stoltzfus J, Bart S, Lok J
PLoS Pathog
. 2014 Jul;
10(7):e1004235.
PMID: 25010340
The infectious form of the parasitic nematode Strongyloides stercoralis is a developmentally arrested third-stage larva (L3i), which is morphologically similar to the developmentally arrested dauer larva in the free-living nematode...
10.
Massey Jr H, Ranjit N, Stoltzfus J, Lok J
Int J Parasitol
. 2013 Mar;
43(7):515-20.
PMID: 23500073
We hypothesise that developmental arrest in infectious larvae of parasitic nematodes is regulated by signalling pathways homologous to Caenorhabditis elegans DAF (dauer formation) pathways. Alignment of Strongyloides stercoralis (Ss) DAF-2...