Jonathan D Schepper
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Explore the profile of Jonathan D Schepper including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
405
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Recent Articles
1.
Chargo N, Schepper J, Rios-Arce N, Kang H, Gardinier J, Parameswaran N, et al.
JBMR Plus
. 2023 Dec;
7(12):e10805.
PMID: 38130770
Glucocorticoids (GCs) are commonly used anti-inflammatory medications with significant side effects, including glucocorticoid-induced osteoporosis (GIO). We have previously demonstrated that chronic subcutaneous GC treatment in mice leads to gut barrier...
2.
Rios-Arce N, Schepper J, Dagenais A, Schaefer L, Daly-Seiler C, Gardinier J, et al.
Bone
. 2020 Feb;
134:115269.
PMID: 32061677
Recent studies in mouse models have shown that gut microbiota significantly influences bone health. We demonstrated that 2-week oral treatment with broad spectrum antibiotics followed by 4 weeks of recovery...
3.
Schepper J, Collins F, Rios-Arce N, Kang H, Schaefer L, Gardinier J, et al.
J Bone Miner Res
. 2019 Dec;
35(4):801-820.
PMID: 31886921
Glucocorticoids (GCs) are potent immune-modulating drugs with significant side effects, including glucocorticoid-induced osteoporosis (GIO). GCs directly induce osteoblast and osteocyte apoptosis but also alter intestinal microbiota composition. Although the gut...
4.
Collins F, Rios-Arce N, Schepper J, Jones A, Schaefer L, Britton R, et al.
Sci Rep
. 2019 Oct;
9(1):14708.
PMID: 31605025
Oral treatment with probiotic bacteria has been shown to prevent bone loss in multiple models of osteoporosis. In previous studies we demonstrated that oral administration of Lactobacillus reuteri in healthy...
5.
McCabe L, Irwin R, Tekalur A, Evans C, Schepper J, Parameswaran N, et al.
Bone
. 2019 Aug;
127:677-678.
PMID: 31445666
No abstract available.
6.
Schepper J, Collins F, Rios-Arce N, Raehtz S, Schaefer L, Gardinier J, et al.
J Bone Miner Res
. 2019 Jan;
34(4):681-698.
PMID: 30690795
Antibiotic treatment, commonly prescribed for bacterial infections, depletes and subsequently causes long-term alterations in intestinal microbiota composition. Knowing the importance of the microbiome in the regulation of bone density, we...
7.
McCabe L, Irwin R, Tekalur A, Evans C, Schepper J, Parameswaran N, et al.
Bone
. 2018 Apr;
118:20-31.
PMID: 29604350
High fat diets can have detrimental effects on the skeleton as well as cause intestinal dysbiosis. Exercise prevents high fat (HF) diet-induced obesity and also improves bone density and prevents...
8.
Schepper J, Irwin R, Kang J, Dagenais K, Lemon T, Shinouskis A, et al.
Adv Exp Med Biol
. 2017 Nov;
1033:225-247.
PMID: 29101658
The intestinal environment is linked to an array of conditions and diseases, including osteoporosis. Human and animal studies indicate that probiotics can benefit intestinal health and may provide a useful...
9.
Rios-Arce N, Collins F, Schepper J, Steury M, Raehtz S, Mallin H, et al.
Adv Exp Med Biol
. 2017 Nov;
1033:151-183.
PMID: 29101655
The intestinal epithelial barrier plays an essential role in maintaining host homeostasis. The barrier regulates nutrient absorption as well as prevents the invasion of pathogenic bacteria in the host. It...
10.
Collins F, Schepper J, Rios-Arce N, Steury M, Kang H, Mallin H, et al.
Adv Exp Med Biol
. 2017 Nov;
1033:59-94.
PMID: 29101652
In recent years a link between the gastrointestinal tract and bone health has started to gain significant attention. Dysbiosis of the intestinal microbiota has been linked to the pathology of...