Jonathan C Howell
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Explore the profile of Jonathan C Howell including associated specialties, affiliations and a list of published articles.
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17
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754
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Recent Articles
11.
Watson C, Mahe M, Munera J, Howell J, Sundaram N, Poling H, et al.
Nat Med
. 2014 Oct;
20(11):1310-4.
PMID: 25326803
Differentiation of human pluripotent stem cells (hPSCs) into organ-specific subtypes offers an exciting avenue for the study of embryonic development and disease processes, for pharmacologic studies and as a potential...
12.
McCracken K, Howell J, Wells J, Spence J
Nat Protoc
. 2011 Nov;
6(12):1920-8.
PMID: 22082986
Here we describe a protocol for generating 3D human intestinal tissues (called organoids) in vitro from human pluripotent stem cells (hPSCs). To generate intestinal organoids, pluripotent stem cells are first...
13.
Howell J, Wells J
Regen Med
. 2011 Nov;
6(6):743-55.
PMID: 22050526
Intestinal resection and malformations in adult and pediatric patients result in devastating consequences. Unfortunately, allogeneic transplantation of intestinal tissue into patients has not been met with the same measure of...
14.
Case J, Horvath T, Howell J, Yoder M, March K, Srour E
Ann N Y Acad Sci
. 2005 Jun;
1044:183-200.
PMID: 15958712
Pluripotent stem cells (PSCs) with transdifferentiation capacity may provide useful therapeutic modalities in the areas of cellular restoration and regenerative medicine. The utility of PSCs depends on their ability to...
15.
Howell J, Lee W, Morrison P, Zhong J, Yoder M, Srour E
Ann N Y Acad Sci
. 2003 Jun;
996:158-73.
PMID: 12799294
Pluripotential stem cells (PSCs) have been recently described in many tissues including skeletal muscle, brain, and bone marrow. However, the true nature of these cells is still unclear, and their...
16.
Royer C, Howell J, Morrison P, Srour E, Yoder M
In Vitro Cell Dev Biol Anim
. 2003 Apr;
38(9):512-7.
PMID: 12703978
A stem cell population isolated from murine skeletal muscle has recently been shown to differentiate into hematopoietic cells after transplantation in vivo. In the present study, we tested the hypothesis...
17.
Howell J, Yoder M, Srour E
Exp Hematol
. 2002 Aug;
30(8):915-24.
PMID: 12160843
Objective: Somatic stem cells, which are poorly defined in postnatal mammalian tissues, are attractive candidates for examination of stem cell plasticity. Our goal was to determine the identity of neonatal...