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Jonas Adrian

Explore the profile of Jonas Adrian including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 55
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Recent Articles
1.
Kuiper J, Krause J, Potgeter L, Adrian J, Hauck C
J Cell Sci . 2023 Jun; 136(11). PMID: 37264948
Opsonin-independent phagocytosis mediated by human carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) has evolved to control a subset of human-restricted bacterial pathogens. CEACAM3 engagement triggers rapid GTP-loading of the small...
2.
Goob G, Adrian J, Cossu C, Hauck C
J Biol Chem . 2022 Jul; 298(9):102269. PMID: 35850306
Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) is a human granulocyte receptor mediating the efficient phagocytosis of a subset of human-restricted bacterial pathogens. Its function depends on phosphorylation of a...
3.
Bonsignore P, Kuiper J, Adrian J, Goob G, Hauck C
Front Immunol . 2020 Mar; 10:3160. PMID: 32117212
Phagocytosis is one of the key innate defense mechanisms executed by specialized cells in multicellular animals. Recent evidence suggests that a particular phagocytic receptor expressed by human polymorphonuclear granulocytes, the...
4.
Adrian J, Bonsignore P, Hammer S, Frickey T, Hauck C
Curr Biol . 2019 Feb; 29(4):616-630.e5. PMID: 30744974
The selective pressure by infectious agents is a major driving force in the evolution of humans and other mammals. Members of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family serve...
5.
Delgado Tascon J, Adrian J, Kopp K, Scholz P, Tschan M, Kuespert K, et al.
J Leukoc Biol . 2015 Jan; 97(3):521-31. PMID: 25567962
Human granulocytes express several glycoproteins of the CEACAM family. One family member, CEACAM3, operates as a single-chain phagocytic receptor, initiating the detection, internalization, and destruction of a limited set of...