Christof R Hauck
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Explore the profile of Christof R Hauck including associated specialties, affiliations and a list of published articles.
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78
Citations
2567
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Recent Articles
1.
Fleckenstein J, Najjar S, Zimmermann W, Hauck C, Nguyen Q, Mejias-Luque R, et al.
Eur J Clin Invest
. 2024 Dec;
54 Suppl 2:e14355.
PMID: 39674873
No abstract available.
2.
Baade T, Michaelis M, Prestel A, Paone C, Klishin N, Herbinger M, et al.
PLoS Biol
. 2024 Sep;
22(9):e3002757.
PMID: 39231388
Integrins are fundamental for cell adhesion and the formation of focal adhesions (FA). Accordingly, these receptors guide embryonic development, tissue maintenance, and haemostasis but are also involved in cancer invasion...
3.
Shi Y, Muenzner P, Schanz-Jurinka S, Hauck C
Microbiol Spectr
. 2024 Feb;
12(4):e0200623.
PMID: 38358281
The gram-positive bacterium can invade non-professional phagocytic cells by associating with the plasma protein fibronectin to exploit host cell integrins. Integrin-mediated internalization of these pathogens is facilitated by the local...
4.
Kuiper J, Gregg H, Schuber M, Klein J, Hauck C
Eur J Cell Biol
. 2024 Jan;
103(1):151384.
PMID: 38215579
Phagocytosis, an innate defense mechanism of multicellular animals, is initiated by specialized surface receptors. A phagocytic receptor expressed by human polymorphonuclear granulocytes, the major professional phagocytes in our body, is...
5.
Kuiper J, Krause J, Potgeter L, Adrian J, Hauck C
J Cell Sci
. 2023 Jun;
136(11).
PMID: 37264948
Opsonin-independent phagocytosis mediated by human carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) has evolved to control a subset of human-restricted bacterial pathogens. CEACAM3 engagement triggers rapid GTP-loading of the small...
6.
Goob G, Adrian J, Cossu C, Hauck C
J Biol Chem
. 2022 Jul;
298(9):102269.
PMID: 35850306
Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) is a human granulocyte receptor mediating the efficient phagocytosis of a subset of human-restricted bacterial pathogens. Its function depends on phosphorylation of a...
7.
Grimm T, Herbinger M, Kruger L, Muller S, Mayer T, Hauck C
Cell Chem Biol
. 2022 Apr;
29(6):930-946.e9.
PMID: 35443151
Phosphatase PPM1F is a regulator of cell adhesion by fine-tuning integrin activity and actin cytoskeleton structures. Elevated expression of this enzyme in human tumors is associated with high invasiveness, enhanced...
8.
Seumen C, Tomasiunaite U, Legler D, Hauck C
Sci Rep
. 2021 Dec;
11(1):24414.
PMID: 34952917
The exquisite specificity of Toll-like receptors (TLRs) to sense microbial molecular signatures is used as a powerful tool to pinpoint microbial contaminants. Various cellular systems, from native human blood cells...
9.
Mix A, Goob G, Sontowski E, Hauck C
Genes Immun
. 2021 Sep;
22(5-6):247-254.
PMID: 34588625
Pathogenic bacteria have evolved a variety of highly selective adhesins allowing these microbes to engage specific surface determinants of their eukaryotic host cells. Receptor clustering induced by the multivalent microorganisms...
10.
Shi Y, Berking A, Baade T, Legate K, Fassler R, Hauck C
Mol Microbiol
. 2021 Sep;
116(5):1249-1267.
PMID: 34519119
Staphylococcus aureus, a Gram-positive pathogen, invades cells mainly in an integrin-dependent manner. As the activity or conformation of several integrin-associated proteins can be regulated by phosphatidylinositol-4,5-bisphosphate (PI-4,5-P ), we investigated...