Jon P Durkin
Overview
Explore the profile of Jon P Durkin including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
172
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0
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Recent Articles
1.
Wang Y, Small D, Stanimirovic D, Morley P, Durkin J
Nature
. 2017 Dec;
554(7692):392.
PMID: 29258299
This corrects the article DOI: 10.1038/39062.
2.
Shaw T, LaCasse E, Durkin J, Vanderhyden B
Int J Cancer
. 2007 Nov;
122(6):1430-4.
PMID: 18027851
A hallmark of cancer cells is an ability to evade apoptosis. Overexpression and/or activating mutations of prosurvival molecules such as the X-linked inhibitor of apoptosis (XIAP) contribute to this inappropriate...
3.
LaCasse E, Cherton-Horvat G, Hewitt K, Jerome L, Morris S, Kandimalla E, et al.
Clin Cancer Res
. 2006 Sep;
12(17):5231-41.
PMID: 16951243
Purpose: Cancer cells can use X-linked inhibitor of apoptosis (XIAP) to evade apoptotic cues, including chemotherapy. The antitumor potential of AEG35156, a novel second-generation antisense oligonucleotide directed toward XIAP, was...
4.
McManus D, Lefebvre C, Cherton-Horvat G, St-Jean M, Kandimalla E, Agrawal S, et al.
Oncogene
. 2004 Sep;
23(49):8105-17.
PMID: 15378029
Stable expression of short-hairpin RNAs (shRNAs) directed against the X-linked inhibitor of apoptosis (XIAP) resulted in the generation of three MDA-MB-231 cell lines (XIAP shRNA cells) with reductions in XIAP...
5.
Hu Y, Cherton-Horvat G, Dragowska V, Baird S, Korneluk R, Durkin J, et al.
Clin Cancer Res
. 2003 Jul;
9(7):2826-36.
PMID: 12855663
Activation of programmed cell death in cancer cells offers novel and potentially useful approaches to improving patient responses to conventional chemotherapy. X-linked inhibitor of apoptosis (XIAP), is the most potent...