Jon Kosek
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Explore the profile of Jon Kosek including associated specialties, affiliations and a list of published articles.
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10
Citations
364
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Recent Articles
1.
Salazar N, Carlson J, Huang K, Zheng Y, Oderup C, Gross J, et al.
Mol Ther
. 2018 Apr;
26(5):1354-1365.
PMID: 29606504
Glioblastoma (GBM) is the least treatable type of brain tumor, afflicting over 15,000 people per year in the United States. Patients have a median survival of 16 months, and over...
2.
Lee Y, Smith D, Rao V, Siegel R, Kosek J, Glaser C, et al.
Case Rep Crit Care
. 2014 May;
2011:562516.
PMID: 24826323
Acute necrotizing encephalopathy (ANE) is a severe neurological complication of influenza infection, including H1N1 influenza. Many cases of ANE have been reported in the pediatric literature, but very few cases...
3.
Wang A, Wysong A, Nord K, Egbert B, Kosek J
Am J Dermatopathol
. 2013 Mar;
36(10):853-5.
PMID: 23503318
Chromhidrosis is a rare idiopathic disorder characterized by colored secretions most typically from the malar cheeks, axilla, or areolar regions. Histologically, chromhidrosis is notable for glandular structures with decapitation secretion...
4.
Zayed M, Kosek J, Wren S
Rare Tumors
. 2012 Feb;
3(4):e43.
PMID: 22355498
A 57-year-old with a 9-year history of increased abdominal girth, presented with increased abdominal pain, anemia, and acute renal failure. His past medical history was only remarkable for a previous...
5.
Jiang X, Khan M, Tian W, Beilke J, Natarajan R, Kosek J, et al.
J Clin Invest
. 2011 May;
121(6):2336-49.
PMID: 21606594
Chronic rejection, manifested as small airway fibrosis (obliterative bronchiolitis [OB]), is the main obstacle to long-term survival in lung transplantation. Recent studies demonstrate that the airways involved in a lung...
6.
Zhang Y, Guo H, Kwan H, Wang J, Kosek J, Lu B
Neuron
. 2007 Jan;
53(2):201-15.
PMID: 17224403
Targeting of synaptic molecules to their proper location is essential for synaptic differentiation and plasticity. PSD-95/Dlg proteins have been established as key components of the postsynapse. However, the molecular mechanisms...
7.
Yang Y, Gehrke S, Haque M, Imai Y, Kosek J, Yang L, et al.
Proc Natl Acad Sci U S A
. 2005 Sep;
102(38):13670-5.
PMID: 16155123
Parkinson's disease (PD) is the most common movement disorder characterized by dopaminergic dysfunction and degeneration. The cause of most PD cases is unknown, although postmortem studies have implicated the involvement...
8.
Patterson A, Zhu W, Chow A, Agrawal R, Kosek J, Xiao R, et al.
Crit Care Med
. 2004 Apr;
32(4):1041-8.
PMID: 15071399
Objective: The sympathetic nervous system enhances cardiac muscle function by activating beta adrenergic receptors (betaARs). Recent studies suggest that chronic betaAR stimulation is detrimental, however, and that it may play...
9.
Gorti G, Lo J, Falsafi S, Kosek J, Quan S, Khuu D, et al.
Arch Otolaryngol Head Neck Surg
. 2003 Aug;
129(8):889-93.
PMID: 12925350
Objective: To generate in vitro hyaline cartilage from cryogenically preserved human septal chondrocytes in a simulated microgravity environment on a 3-dimensional biodegradable scaffolding material. Methods: In this experiment, cryogenically frozen...
10.
Brum P, Kosek J, Patterson A, Bernstein D, Kobilka B
Am J Physiol Heart Circ Physiol
. 2002 Oct;
283(5):H1838-45.
PMID: 12384461
alpha(2A)-Adrenergic receptors (ARs) in the midbrain regulate sympathetic nervous system activity, and both alpha(2A)-ARs and alpha(2C)-ARs regulate catecholamine release from sympathetic nerve terminals in cardiac tissue. Disruption of both alpha(2A)-...