Jon F Edd
Overview
Explore the profile of Jon F Edd including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
968
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0
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Recent Articles
1.
Mishra A, Huang S, Dubash T, Burr R, Edd J, Wittner B, et al.
Nat Commun
. 2025 Jan;
16(1):32.
PMID: 39746954
Circulating Tumor Cells (CTCs) in blood encompass DNA, RNA, and protein biomarkers, but clinical utility is limited by their rarity. To enable tumor epitope-agnostic interrogation of large blood volumes, we...
2.
Mishra A, Huang S, Dubash T, Burr R, Edd J, Wittner B, et al.
bioRxiv
. 2024 Apr;
PMID: 38559183
Circulating Tumor Cells (CTCs), interrogated by sampling blood from patients with cancer, contain multiple analytes, including intact RNA, high molecular weight DNA, proteins, and metabolic markers. However, the clinical utility...
3.
Gopinathan K, Mishra A, Mutlu B, Edd J, Toner M
Nature
. 2023 Oct;
622(7984):735-741.
PMID: 37880436
Microfluidics have enabled notable advances in molecular biology, synthetic chemistry, diagnostics and tissue engineering. However, there has long been a critical need in the field to manipulate fluids and suspended...
4.
Gopinathan K, Mishra A, Mutlu B, Edd J, Toner M
bioRxiv
. 2023 Jul;
PMID: 37398240
Microfluidics have enabled significant advances in molecular biology , synthetic chemistry , diagnostics , and tissue engineering . However, there has long been a critical need in the field to...
5.
Micalizzi D, Che D, Nicholson B, Edd J, Desai N, Lang E, et al.
Proc Natl Acad Sci U S A
. 2022 Oct;
119(43):e2209563119.
PMID: 36256815
The successful application of antibody-based therapeutics in either primary or metastatic cancer depends upon the selection of rare cell surface epitopes that distinguish cancer cells from surrounding normal epithelial cells....
6.
Edd J, Mishra A, Smith K, Kapur R, Maheswaran S, Haber D, et al.
iScience
. 2022 Jul;
25(8):104696.
PMID: 35880043
Circulating tumor cells (CTCs) enter the vasculature from solid tumors and disseminate widely to initiate metastases. Mining the metastatic-enriched molecular signatures of CTCs before, during, and after treatment holds unique...
7.
Burr R, Edd J, Chirn B, Mishra A, Haber D, Toner M, et al.
Methods Mol Biol
. 2022 Feb;
2471:309-321.
PMID: 35175606
The ability to isolate and analyze rare circulating tumor cells (CTCs) holds the potential to increase our understanding of cancer evolution and allows monitoring of disease and therapeutic responses through...
8.
Sakuma M, Wang X, Ellett F, Edd J, Babatunde K, Viens A, et al.
Lab Chip
. 2022 Jan;
22(5):936-944.
PMID: 35084421
Neutrophils are the largest population of white blood cells in the circulation, and their primary function is to protect the body from microbes. They can release the chromatin in their...
9.
Mishra A, Dubash T, Edd J, Jewett M, Garre S, Karabacak N, et al.
Proc Natl Acad Sci U S A
. 2020 Jul;
117(29):16839-16847.
PMID: 32641515
Circulating tumor cell (CTC)-based liquid biopsies provide unique opportunities for cancer diagnostics, treatment selection, and response monitoring, but even with advanced microfluidic technologies for rare cell detection the very low...
10.
Mutlu B, Dubash T, Dietsche C, Mishra A, Ozbey A, Keim K, et al.
Lab Chip
. 2020 Apr;
20(9):1612-1620.
PMID: 32301448
Multicellular clusters in circulation can exhibit a substantially different function and biomarker significance compared to individual cells. Notably, clusters of circulating tumor cells (CTCs) are much more effective initiators of...