Jon Celay
Overview
Explore the profile of Jon Celay including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
255
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0
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Recent Articles
1.
Felix-Soriano E, Sainz N, Gil-Iturbe E, Castilla-Madrigal R, Celay J, Fernandez-Galilea M, et al.
J Physiol Biochem
. 2023 May;
79(2):451-465.
PMID: 37204588
Obesity exacerbates aging-induced adipose tissue dysfunction. This study aimed to investigate the effects of long-term exercise on inguinal white adipose tissue (iWAT) and interscapular brown adipose tissue (iBAT) of aged...
2.
Larrayoz M, Garcia-Barchino M, Celay J, Etxebeste A, Jimenez M, Perez C, et al.
Nat Med
. 2023 Mar;
29(3):632-645.
PMID: 36928817
The historical lack of preclinical models reflecting the genetic heterogeneity of multiple myeloma (MM) hampers the advance of therapeutic discoveries. To circumvent this limitation, we screened mice engineered to carry...
3.
Sacco A, Desantis V, Celay J, Giustini V, Rigali F, Savino F, et al.
Blood
. 2023 Feb;
141(21):2615-2628.
PMID: 36735903
Recent investigations have improved our understanding of the molecular aberrations supporting Waldenström macroglobulinemia (WM) biology; however, whether the immune microenvironment contributes to WM pathogenesis remains unanswered. First, we showed how...
4.
Felix-Soriano E, Sainz N, Fernandez-Galilea M, Gil-Iturbe E, Celay J, Martinez-Climent J, et al.
J Nutr Biochem
. 2022 Sep;
111:109153.
PMID: 36150680
This study aimed to characterize the potential beneficial effects of chronic docosahexaenoic acid (DHA) supplementation on restoring subcutaneous white adipose tissue (scWAT) plasticity in obese aged female mice. Two-month-old female...
5.
Rodriguez S, Celay J, Goicoechea I, Jimenez C, Botta C, Garcia-Barchino M, et al.
Sci Adv
. 2022 Jan;
8(3):eabl4644.
PMID: 35044826
Normal cell counterparts of solid and myeloid tumors accumulate mutations years before disease onset; whether this occurs in B lymphocytes before lymphoma remains uncertain. We sequenced multiple stages of the...
6.
Blanco-Luquin I, Lazcoz P, Celay J, Castresana J, Encio I
Pharmaceuticals (Basel)
. 2021 Nov;
14(11).
PMID: 34832966
Neuroblastoma is the most frequent malignant extracranial solid tumor of infancy. The overall objective of this work consists of determining the presence of alterations in the p53/MDM2/p14ARF signaling pathway in...
7.
Fresquet V, Garcia-Barchino M, Larrayoz M, Celay J, Vicente C, Fernandez-Galilea M, et al.
Cancer Discov
. 2020 Dec;
11(5):1268-1285.
PMID: 33355179
For millions of years, endogenous retroelements have remained transcriptionally silent within mammalian genomes by epigenetic mechanisms. Modern anticancer therapies targeting the epigenetic machinery awaken retroelement expression, inducing antiviral responses that...
8.
Goicoechea I, Puig N, Cedena M, Burgos L, Cordon L, Vidriales M, et al.
Blood
. 2020 Jul;
137(1):49-60.
PMID: 32693406
Patients with multiple myeloma (MM) carrying standard- or high-risk cytogenetic abnormalities (CAs) achieve similar complete response (CR) rates, but the later have inferior progression-free survival (PFS). This questions the legitimacy...
9.
Pascual M, Mena-Varas M, Robles E, Garcia-Barchino M, Panizo C, Hervas-Stubbs S, et al.
Blood
. 2019 Apr;
133(22):2401-2412.
PMID: 30975638
Refractory or relapsed diffuse large B-cell lymphoma (DLBCL) often associates with the activated B-cell-like (ABC) subtype and genetic alterations that drive constitutive NF-κB activation and impair B-cell terminal differentiation. Here,...
10.
Garcia-Barchino M, Sarasquete M, Panizo C, Morscio J, Martinez A, Alcoceba M, et al.
J Pathol
. 2018 Feb;
245(1):61-73.
PMID: 29464716
The increased risk of Richter transformation (RT) in patients with chronic lymphocytic leukaemia (CLL) due to Epstein-Barr virus (EBV) reactivation during immunosuppressive therapy with fludarabine other targeted agents remains controversial....