Jose A Martinez-Climent
Overview
Explore the profile of Jose A Martinez-Climent including associated specialties, affiliations and a list of published articles.
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Articles
52
Citations
1430
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Recent Articles
1.
Felix-Soriano E, Sainz N, Gil-Iturbe E, Castilla-Madrigal R, Celay J, Fernandez-Galilea M, et al.
J Physiol Biochem
. 2023 May;
79(2):451-465.
PMID: 37204588
Obesity exacerbates aging-induced adipose tissue dysfunction. This study aimed to investigate the effects of long-term exercise on inguinal white adipose tissue (iWAT) and interscapular brown adipose tissue (iBAT) of aged...
2.
Larrayoz M, Garcia-Barchino M, Celay J, Etxebeste A, Jimenez M, Perez C, et al.
Nat Med
. 2023 Mar;
29(3):632-645.
PMID: 36928817
The historical lack of preclinical models reflecting the genetic heterogeneity of multiple myeloma (MM) hampers the advance of therapeutic discoveries. To circumvent this limitation, we screened mice engineered to carry...
3.
Melchor J, Garcia-Lacarte M, Grijalba S, Arnaiz-Leche A, Pascual M, Panizo C, et al.
J Immunother Cancer
. 2023 Feb;
11(2).
PMID: 36854569
Background: Approximately one-third of diffuse large B cell lymphoma (DLBCL) patients exhibit co-expression of MYC and BCL2 (double-expressor lymphoma, DEL) and have a dismal prognosis. Targeted inhibition of the anti-apoptotic...
4.
Sacco A, Desantis V, Celay J, Giustini V, Rigali F, Savino F, et al.
Blood
. 2023 Feb;
141(21):2615-2628.
PMID: 36735903
Recent investigations have improved our understanding of the molecular aberrations supporting Waldenström macroglobulinemia (WM) biology; however, whether the immune microenvironment contributes to WM pathogenesis remains unanswered. First, we showed how...
5.
Peris I, Romero-Murillo S, Martinez-Balsalobre E, Farrington C, Arriazu E, Marcotegui N, et al.
Blood
. 2022 Dec;
141(9):1047-1059.
PMID: 36455198
Venetoclax combination therapies are becoming the standard of care in acute myeloid leukemia (AML). However, the therapeutic benefit of these drugs in older/unfit patients is limited to only a few...
6.
Felix-Soriano E, Sainz N, Fernandez-Galilea M, Gil-Iturbe E, Celay J, Martinez-Climent J, et al.
J Nutr Biochem
. 2022 Sep;
111:109153.
PMID: 36150680
This study aimed to characterize the potential beneficial effects of chronic docosahexaenoic acid (DHA) supplementation on restoring subcutaneous white adipose tissue (scWAT) plasticity in obese aged female mice. Two-month-old female...
7.
Fresquet V, Garcia-Barchino M, Larrayoz M, Celay J, Vicente C, Fernandez-Galilea M, et al.
Cancer Discov
. 2020 Dec;
11(5):1268-1285.
PMID: 33355179
For millions of years, endogenous retroelements have remained transcriptionally silent within mammalian genomes by epigenetic mechanisms. Modern anticancer therapies targeting the epigenetic machinery awaken retroelement expression, inducing antiviral responses that...
8.
Balinas-Gavira C, Rodriguez M, Andrades A, Cuadros M, Alvarez-Perez J, Alvarez-Prado A, et al.
Leukemia
. 2020 Jun;
34(10):2722-2735.
PMID: 32576963
Mutations in genes encoding subunits of the SWI/SNF chromatin remodeling complex are frequently found in different human cancers. While the tumor suppressor function of this complex is widely established in...
9.
Bueno-Costa A, Pineyro D, Soler M, Javierre B, Raurell-Vila H, Subirana-Granes M, et al.
Leukemia
. 2019 Nov;
34(4):1158-1162.
PMID: 31719676
No abstract available.
10.
Martinez-Velez N, Garcia-Moure M, Marigil M, Gonzalez-Huarriz M, Puigdelloses M, Gallego Perez-Larraya J, et al.
Nat Commun
. 2019 May;
10(1):2235.
PMID: 31138805
Pediatric high-grade glioma (pHGG) and diffuse intrinsic pontine gliomas (DIPGs) are aggressive pediatric brain tumors in desperate need of a curative treatment. Oncolytic virotherapy is emerging as a solid therapeutic...