Jolly Mazumdar
Overview
Explore the profile of Jolly Mazumdar including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
901
Followers
0
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Recent Articles
1.
Mak G, Soria J, Blagden S, Plummer R, Fleming R, Nebot N, et al.
Br J Cancer
. 2019 Apr;
120(10):975-981.
PMID: 30992546
Background: Combined focal adhesion kinase (FAK) and MEK inhibition may provide greater anticancer effect than FAK monotherapy. Methods: This dose-finding phase Ib study (adaptive 3 + 3 design) determined the...
2.
Santiago-Walker A, Gagnon R, Mazumdar J, Casey M, Long G, Schadendorf D, et al.
Clin Cancer Res
. 2015 Oct;
22(3):567-74.
PMID: 26446943
Purpose: Tumor-derived circulating cell-free DNA (cfDNA) is a potential alternative source from which to derive tumor mutation status. cfDNA data from four clinical studies of the BRAF inhibitor (BRAFi) dabrafenib...
3.
Ascierto P, Minor D, Ribas A, Lebbe C, OHagan A, Arya N, et al.
J Clin Oncol
. 2013 Aug;
31(26):3205-11.
PMID: 23918947
Purpose: Dabrafenib (GSK2118436) is a potent inhibitor of mutated BRAF kinase. Our multicenter, single-arm, phase II study assessed the safety and clinical activity of dabrafenib in BRAF(V600E/K) mutation-positive metastatic melanoma...
4.
Mazumdar J, OBrien W, Johnson R, LaManna J, Chavez J, Klein P, et al.
Nat Cell Biol
. 2010 Sep;
12(10):1007-13.
PMID: 20852629
Stem cells reside in specialized microenvironments or 'niches' that regulate their function. In vitro studies using hypoxic culture conditions (<5% O2) have revealed strong regulatory links between O2 availability and...
5.
Mazumdar J, Hickey M, Pant D, Durham A, Sweet-Cordero A, Vachani A, et al.
Proc Natl Acad Sci U S A
. 2010 Jul;
107(32):14182-7.
PMID: 20660313
Non-small cell lung cancer (NSCLC) is the leading cause of cancer deaths worldwide. The oxygen-sensitive hypoxia inducible factor (HIF) transcriptional regulators HIF-1alpha and HIF-2alpha are overexpressed in many human NSCLCs,...
6.
Mazumdar J, Dondeti V, Simon M
J Cell Mol Med
. 2009 Nov;
13(11-12):4319-28.
PMID: 19900215
Cellular properties are influenced by complex factors inherent to their microenvironments. While oxygen deprivation (hypoxia) occurs in tumours because of rapid cell proliferation and aberrant blood vessel formation, embryonic cells...
7.
Mazumdar J, Striepen B
Eukaryot Cell
. 2007 Aug;
6(10):1727-35.
PMID: 17715365
No abstract available.
8.
Mazumdar J, Wilson E, Masek K, Hunter C, Striepen B
Proc Natl Acad Sci U S A
. 2006 Aug;
103(35):13192-7.
PMID: 16920791
Apicomplexan parasites are the cause of numerous important human diseases including malaria and AIDS-associated opportunistic infections. Drug treatment for these diseases is not satisfactory and is threatened by resistance. The...