Joke Meeus
Overview
Explore the profile of Joke Meeus including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
157
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Recent Articles
1.
Rodriguez-Nogales C, Meeus J, Thonus G, Corveleyn S, Allemann E, Jordan O
Drug Deliv
. 2023 Nov;
30(1):2284683.
PMID: 37994039
Nano- and micro-technologies can salvage drugs with very low solubility that were doomed to pre-clinical and clinical failure. A unique design approach to develop drug nanocrystals (NCs) loaded in extended...
2.
Ousset A, Bassand C, Chavez P, Meeus J, Robin F, Schubert M, et al.
Pharm Dev Technol
. 2018 Oct;
24(5):560-574.
PMID: 30303440
The present study details the development of a small-scale spray-drying approach for the routine screening of amorphous solid dispersions (ASDs). This strategy aims to overcome the limitations of standard screening...
3.
Ousset A, Chavez P, Meeus J, Robin F, Schubert M, Somville P, et al.
Pharmaceutics
. 2018 Mar;
10(1).
PMID: 29518936
The evaluation of drug-polymer miscibility in the early phase of drug development is essential to ensure successful amorphous solid dispersion (ASD) manufacturing. This work investigates the comparison of thermodynamic models,...
4.
Meeus J, Lenaerts M, Scurr D, Amssoms K, Davies M, Roberts C, et al.
J Pharm Sci
. 2015 Feb;
104(4):1451-60.
PMID: 25648704
For ternary solid dispersions, it is indispensable to characterize their structure, phase behavior, and the spatial distribution of the dispersed drug as this might influence the release profile and/or stability...
5.
Meeus J, Scurr D, Amssoms K, Wuyts K, Annaert P, Davies M, et al.
J Control Release
. 2014 Dec;
199:1-9.
PMID: 25485732
At present no scientific rationale exists for selecting a particular enabling strategy to formulate a poorly water-soluble drug, although this is crucial as it will influence the in vivo performance...
6.
Meeus J, Scurr D, Appeltans B, Amssoms K, Annaert P, Davies M, et al.
Eur J Pharm Biopharm
. 2014 Dec;
90:22-9.
PMID: 25448071
Understanding and controlling the in vitro release behavior of a formulation is a first step toward rationalized selection of a solubility enhancing formulation strategy with a desired release profile in...
7.
Meeus J, Scurr D, Chen X, Amssoms K, Davies M, Roberts C, et al.
Pharm Res
. 2014 Oct;
32(4):1407-16.
PMID: 25319105
Purpose: Miscibility of the different compounds that make up a solid dispersion based formulation play a crucial role in the drug release profile and physical stability of the solid dispersion...
8.
Vandenheuvel D, Meeus J, Lavigne R, Van den Mooter G
Int J Pharm
. 2014 Jun;
472(1-2):202-5.
PMID: 24950368
Spray drying is a valuable technique in pharmaceutical dosage formulation, capable of producing amorphous, spherical powders, suitable for pulmonary deposition and further downstream processing. In this study, we show that...
9.
Meeus J, Scurr D, Amssoms K, Davies M, Roberts C, Van den Mooter G
Mol Pharm
. 2013 Jul;
10(8):3213-24.
PMID: 23844639
In view of the increasing interest in injectable controlled release formulations for the treatment of chronic diseases, injectable polymeric microspheres consisting of a surface layer of poly(lactic-co-glycolic acid) (PLGA) and...
10.
Paudel A, Worku Z, Meeus J, Guns S, Van den Mooter G
Int J Pharm
. 2012 Jul;
453(1):253-84.
PMID: 22820134
Spray drying is an efficient technology for solid dispersion manufacturing since it allows extreme rapid solvent evaporation leading to fast transformation of an API-carrier solution to solid API-carrier particles. Solvent...