Johnny Sze
Overview
Explore the profile of Johnny Sze including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
472
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0
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Recent Articles
1.
Wang Z, Lu G, Sze J, Liu Y, Lin S, Yao H, et al.
Mol Neurobiol
. 2017 Nov;
55(7):5879-5888.
PMID: 29101647
Stroke causes death or long-term disabilities and threatens the general health of the population worldwide. Recent studies have suggested that miRNAs are dysregulated and can be used as biomarkers for...
2.
Su X, Chan A, Lu G, Lin M, Sze J, Zhou J, et al.
PLoS One
. 2015 Dec;
10(12):e0144724.
PMID: 26675167
Background: Aneurysmal subarachnoid hemorrhage (SAH) is a highly morbid and fatal condition with high rate of cognitive impairment and negative impact in quality of life among survivors. Delayed cerebral infarction...
3.
Xu Z, Jin J, Siu L, Yao H, Sze J, Sun H, et al.
Int J Pharm
. 2012 Jan;
426(1-2):182-192.
PMID: 22265912
In this study we describe a novel polymer, mPPS-FA, synthesized as a potential gene transfer vector. To complete mPPS-FA, folic acid was conjugated to a backbone (named mPPS) consisting of...
4.
Xia H, Cheung W, Ng S, Jiang X, Jiang S, Sze J, et al.
J Biol Chem
. 2012 Jan;
287(13):9962-9971.
PMID: 22253443
miR-124 is a brain-enriched microRNA that plays a crucial role in neural development and has been shown to be down-regulated in glioma and medulloblastoma, suggesting its possible involvement in brain...
5.
MYC protein inhibits transcription of the microRNA cluster MC-let-7a-1~let-7d via noncanonical E-box
Wang Z, Lin S, Li J, Xu Z, Yao H, Zhu X, et al.
J Biol Chem
. 2011 Sep;
286(46):39703-14.
PMID: 21903590
The human microRNA cluster MC-let-7a-1∼let-7d, with three members let-7a-1, let-7f-1, and let-7d, is an important cluster of the let-7 family. These microRNAs play critical roles in regulating development and carcinogenesis....
6.
Yao H, Ng S, Huo L, Chow B, Shen Z, Yang M, et al.
Mol Cancer Ther
. 2011 Apr;
10(6):1082-92.
PMID: 21518728
Interleukin-2 (IL-2) has been shown to possess antitumor activity in numerous preclinical and clinical studies. However, the short half-life of recombinant IL-2 protein in serum requires repeated high-dose injections, resulting...
7.
Yu F, Ng S, Chow B, Sze J, Lu G, Poon W, et al.
J Neurooncol
. 2010 Sep;
103(2):187-95.
PMID: 20838853
Interferon-induced transmembrane protein 1 (IFITM1) has recently been identified as a new molecular marker in human colorectal cancer. However, its role in glioma carcinogenesis is not known. In this study,...
8.
Xia H, Cheung W, Sze J, Lu G, Jiang S, Yao H, et al.
J Biol Chem
. 2010 Sep;
285(47):36995-7004.
PMID: 20826811
The emerging concept of generating cancer stem cells from epithelial-mesenchymal transition has attracted great interest; however, the factors and molecular mechanisms that govern this putative tumor-initiating process remain largely elusive....
9.
An X, Ng S, Xie D, Zeng Y, Sze J, Wang J, et al.
Eur J Cancer
. 2010 May;
46(9):1752-61.
PMID: 20466538
Cell cycle-related kinase (CCRK) is a newly identified protein kinase homologous to Cdk7. We have previously shown that CCRK is a candidate oncogene in human glioblastoma. However, whether CCRK is...
10.
Xia H, Ng S, Jiang S, Cheung W, Sze J, Bian X, et al.
Biochem Biophys Res Commun
. 2009 Nov;
391(1):535-41.
PMID: 19931509
Nasopharyngeal carcinoma (NPC), a highly metastatic and invasive malignant tumor originating from the nasopharynx, is widely prevalent in Southeast Asia, the Middle East and North Africa. Although viral, dietary and...