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Billy K C Chow

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Articles 110
Citations 1621
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Recent Articles
1.
Nawabjan S, Singh K, G S M, Au-Yeung R, Zhang F, Zhang L, et al.
Food Chem Toxicol . 2024 Dec; 196:115195. PMID: 39667608
The Secretin receptor (SCTR) presents a promising path for hypertension management, with KSD179019 as identified as a Positive Allosteric Modulator (PAM) of SCTR, demonstrating anti-hypertensive effects in animal models. Our...
2.
Kumar M, Choi Y, Wong T, Li P, Chow B
J Eur Acad Dermatol Venereol . 2024 Jul; 39(3):476-486. PMID: 39044547
Chronic spontaneous urticaria (CSU), atopic dermatitis (AD), psoriasis and rosacea are highly prevalent inflammatory skin conditions which impose a significant burden on patients' quality of life. Their pathophysiology is likely...
3.
Su L, Li G, Chow B, Cardoso J
Mol Cell Endocrinol . 2024 Jun; 592:112324. PMID: 38944371
Genomes and transcriptomes from diverse organisms are providing a wealth of data to explore the evolution and origin of neuropeptides and their receptors in metazoans. While most neuropeptide-receptor systems have...
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Wong T, Choi Y, Li P, Chow B, Kumar M
Front Immunol . 2024 May; 15:1406438. PMID: 38817611
Introduction: Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterised by itching, erythema, and epidermal barrier dysfunction. The pathogenesis of AD is complex and multifactorial; however,mast cell (MC) activation...
6.
Duraisamy K, Kumar M, Nawabjan A, Lo E, Hui Lin M, Lefranc B, et al.
Biomed Pharmacother . 2024 Mar; 174:116471. PMID: 38547764
The mast cell receptor Mrgprb2, a mouse orthologue of human Mrgprx2, is known as an inflammatory receptor and its elevated expression is associated with various diseases such as ulcerative colitis....
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Berg P, Jensen T, Andersen J, Svendsen S, Modvig I, Wang T, et al.
J Am Soc Nephrol . 2023 Jun; 34(8):1329-1342. PMID: 37344929
Significance Statement: During acute base excess, the renal collecting duct β -intercalated cells ( β -ICs) become activated to increase urine base excretion. This process is dependent on pendrin and...
8.
Wei J, Han Q, Luo Z, Liu L, Cui J, Tan J, et al.
Natl Sci Rev . 2023 Feb; 10(1):nwac179. PMID: 36845323
Innate social investigation behaviors are critical for animal survival and are regulated by both neural circuits and neuroendocrine factors. Our understanding of how neuropeptides regulate social interest, however, is incomplete...
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Kumar M, Duraisamy K, Annapureddy R, Chan C, Chow B
J Allergy Clin Immunol . 2022 Dec; 151(4):1110-1122. PMID: 36581009
Background: Activation of Mas-related G protein-coupled receptor X2 (MRGPRX2) is a crucial non-IgE pathway for mast cell activation associated with allergic reactions and inflammation. Only a few peptides and small...
10.
Sun Y, Wang Z, Nie C, Xue L, Wang Y, Liu J, et al.
Food Funct . 2022 May; 13(11):6317-6328. PMID: 35611953
Hydroxysafflor yellow A (HSYA) is the main bioactive component of safflower and has been reported to have significant health-promoting abilities. However, the regulation of HSYA on different types of skeletal...