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John Marshal Jayaraj

Explore the profile of John Marshal Jayaraj including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 32
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Recent Articles
1.
Jayaraj J, Muthusamy K
J Biomol Struct Dyn . 2023 May; 42(6):2886-2896. PMID: 37216366
Worldwide, the burden of chronic kidney disease (CKD) has increased rapidly and is a lethal disease. The klotho protein plays a vital role in the regulatory mechanism in the progression...
2.
Jayaraj J, Jothimani M, Palanisamy C, Pentikainen O, Pannipara M, Al-Sehemi A, et al.
Bioinorg Chem Appl . 2022 Mar; 2022:8635054. PMID: 35340421
COVID-19 is more virulent and challenging to human life. In India, the Ministry of AYUSH recommended some strategies through Siddha, homeopathy, and other methods to effectively manage COVID-19 (Guidelines for...
3.
Jayaraj J, Briget Kuriakose B, Hamad Alhazmi A, Muthusamy K
Cell Biochem Funct . 2021 Jul; 39(7):874-885. PMID: 34231237
The development of chronic kidney disease (CKD) drugs remains a challenge due to the variations in the genes. The vitamin D receptor (VDR) and Cytochrome 24A1 (CYP24A1) genetic variants might...
4.
Arokiaraj S, Tajuddin N, Muthusamy K, Jayaraj J, Alagumuthu M
ACS Comb Sci . 2020 Sep; 22(11):608-616. PMID: 32960032
TRAF2 and NCK-interacting kinase (TNIK) is a critical factor in colorectal cancer (CRC) proliferation mediated by signaling. We attempted to identify efficient TNIK inhibitors using computational high-throughput virtual screening (HTVS)...
5.
Jayaraj J, Reteti E, Kesavan C, Muthusamy K
J Biomol Struct Dyn . 2020 May; 39(11):4148-4159. PMID: 32462983
Vitamin D deficiency is one of the common clinical symptoms of severe chronic kidney disease (CKD) patients. Vitamin D receptor (VDR) is a part of the nuclear receptor family exerts...
6.
Loganathan L, Muthusamy K, Jayaraj J, Kajamaideen A, Balthasar J
J Biomol Struct Dyn . 2018 Sep; 37(14):3637-3648. PMID: 30204055
The Wnt/β-catenin pathway plays an important regulatory role in cancer signaling and cell regenerative mechanisms. Its suppression has long been considered as an important challenge of anticancer treatment and management....
7.
Jayaraj J, Krishnasamy G, Lee J, Muthusamy K
J Biomol Struct Dyn . 2018 Apr; 37(7):1700-1714. PMID: 29658431
Vitamin D is a key signalling molecule that plays a vital role in the regulation of calcium phosphate homeostasis and bone remodelling. The circulating biologically active form of vitamin D...