Lakshmanan Loganathan
Overview
Explore the profile of Lakshmanan Loganathan including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
57
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Recent Articles
1.
Carlus F, Sujatha L, Kumar A, Loganathan L, Muthusamy K, Carlus S
Ann Pediatr Cardiol
. 2024 Feb;
16(4):266-275.
PMID: 38343505
Background: Individuals with Down syndrome (DS) have a 40%-60% chance of being born with congenital heart disease (CHD). This indicates that CHD in individuals with DS is not solely caused...
2.
Loganathan L, Sankar J, Rajendran K, Muthusamy K
J Biomol Struct Dyn
. 2023 Oct;
42(24):13411-13420.
PMID: 37897186
The renin enzyme is considered a promising target for hypertension and renal diseases. Over the last three decades, several experimental and theoretical studies have been engaged in the discovery of...
3.
Loganathan L, Jeyaraman J, Muthusamy K
Comb Chem High Throughput Screen
. 2023 May;
27(5):745-753.
PMID: 37202885
Background: Hypertension is notably a serious public health concern due to its high prevalence and strong association with cardiovascular disease and renal failure. It is reported to be the fourth...
4.
Loganathan L, Briget Kuriakose B, Mushfiq S, Muthusamy K
J Cell Biochem
. 2021 Jun;
122(10):1460-1474.
PMID: 34161641
Past several decades, therapeutic investigations lead to the discovery of numerous antihypertensive drugs. Although it has been proved for their potency, altered efficacy is common norms in several conditions due...
5.
Loganathan L, Natarajan K, Muthusamy K
J Biomol Struct Dyn
. 2019 Nov;
38(17):5173-5185.
PMID: 31760854
Cancer is distinguished by uncontrolled cell growth and it is regulated by several environmental and genetic factors. The Wnt β-Catenin signaling pathway has been considered as the most significant colon...
6.
Sivanantham A, Pattarayan D, Rajasekar N, Kannan A, Loganathan L, Bethunaickan R, et al.
Inflamm Res
. 2019 Sep;
68(12):1011-1024.
PMID: 31489459
Background: Polarized macrophages induce fibrosis through multiple mechanisms, including a process termed epithelial-to-mesenchymal transition (EMT). Mesenchymal cells contribute to the excessive accumulation of fibrous connective tissues, leading to organ failure....
7.
Loganathan L, Gopinath K, Sankaranarayanan V, Kukreti R, Rajendran K, Lee J, et al.
Curr Drug Targets
. 2019 Aug;
21(1):18-33.
PMID: 31393243
Background: Hypertension is a prevalent cardiovascular complication caused by genetic and nongenetic factors. Blood pressure (BP) management is difficult because most patients become resistant to monotherapy soon after treatment initiation....
8.
Loganathan L, Muthusamy K
Curr Pharm Des
. 2018 Nov;
24(32):3829-3841.
PMID: 30426891
Worldwide, colorectal cancer takes up the third position in commonly detected cancer and fourth in cancer mortality. Recent progress in molecular modeling studies has led to significant success in drug...
9.
Loganathan L, Muthusamy K, Jayaraj J, Kajamaideen A, Balthasar J
J Biomol Struct Dyn
. 2018 Sep;
37(14):3637-3648.
PMID: 30204055
The Wnt/β-catenin pathway plays an important regulatory role in cancer signaling and cell regenerative mechanisms. Its suppression has long been considered as an important challenge of anticancer treatment and management....
10.
Pattarayan D, Sivanantham A, Krishnaswami V, Loganathan L, Palanichamy R, Natesan S, et al.
J Cell Physiol
. 2017 Aug;
233(3):2513-2525.
PMID: 28771711
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and an irreversible lung disorder characterized by the accumulation of fibroblasts and myofibroblasts in the extracellular matrix. The transforming growth factor-β1 (TGF-β1)-induced...