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John M Slopis

Explore the profile of John M Slopis including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 832
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Recent Articles
21.
Khiewvan B, Macapinlac H, Lev D, McCutcheon I, Slopis J, Al Sannaa G, et al.
Eur J Nucl Med Mol Imaging . 2014 Apr; 41(9):1756-66. PMID: 24699907
Purpose: Our objective was to determine how positron emission tomography (PET)/CT had been used in the clinical treatment of malignant peripheral nerve sheath tumor (MPNST) patients at The University of...
22.
Piotrowski A, Xie J, Liu Y, Poplawski A, Gomes A, Madanecki P, et al.
Nat Genet . 2013 Dec; 46(2):182-7. PMID: 24362817
Constitutional SMARCB1 mutations at 22q11.23 have been found in ∼50% of familial and <10% of sporadic schwannomatosis cases. We sequenced highly conserved regions along 22q from eight individuals with schwannomatosis...
23.
Angelo L, Maxwell D, Wu J, Sun D, Hawke D, McCutcheon I, et al.
Bioorg Med Chem . 2013 Jan; 21(4):932-9. PMID: 23294827
Curcumin (diferuloylmethane) is a potent anti-inflammatory and anti-tumorigenic agent that has shown preclinical activity in diverse cancers. Curcumin up-regulates heat shock protein 70 (hsp70) mRNA in several different cancer cell...
24.
Angelo L, Wu J, Meng F, Sun M, Kopetz S, McCutcheon I, et al.
Mol Cancer Ther . 2011 Sep; 10(11):2094-103. PMID: 21903608
Neurofibromatosis type 2 (NF2) is a genetic condition characterized by inactivation of the NF2 tumor suppressor gene and the development of schwannomas. The NF2 gene product, merlin, is activated (dephosphorylated)...
25.
Lopez G, Torres K, Liu J, Hernandez B, Young E, Belousov R, et al.
Cancer Res . 2010 Nov; 71(1):185-96. PMID: 21084276
Histone deacetylase inhibitors (HDACi) show promise as cancer therapeutics; however, the full scope of their utility remains unknown. Here we report findings that strongly rationalize clinical evaluation of HDACis in...
26.
Rokes C, Ketonen L, Fuller G, Weinberg J, Slopis J, Wolff J
Pediatr Blood Cancer . 2009 Jun; 53(4):672-4. PMID: 19544396
Meningioangiomatosis (MA) is an uncommon brain tumor. The role of imaging techniques is underscored in cases where the tumor location makes resection (or even biopsy) dangerous. We report the case...
27.
Zou C, Smith K, Liu J, Lahat G, Myers S, Wang W, et al.
Ann Surg . 2009 May; 249(6):1014-22. PMID: 19474676
Objective: Improved staging systems for malignant peripheral nerve sheath tumor (MPNST) prognostication and management are needed. Consequently, we sought to identify clinical, pathologic, and molecular predictors of outcome in patients...
28.
Zou C, Smith K, Zhu Q, Liu J, McCutcheon I, Slopis J, et al.
Mol Cancer Ther . 2009 May; 8(5):1157-68. PMID: 19417153
The mammalian target of rapamycin (mTOR) pathway may constitute a potential target for the treatment of malignant peripheral nerve sheath tumors (MPNST). However, investigations of other cancers suggest that mTOR...
29.
Koenig M, Sitton C, Wang M, Slopis J
J Child Neurol . 2008 Nov; 23(11):1347-52. PMID: 18984849
Intracranial hemorrhage during blastic crisis is a rare but critically important occurrence in children with acute lymphoblastic leukemia. This form of hemorrhage has not been described since the advent of...
30.
Billingsley R, Jackson E, Slopis J, Swank P, Mahankali S, Moore 3rd B
J Child Neurol . 2003 Dec; 18(11):731-40. PMID: 14696899
Neurofibromatosis 1 is associated with reading disabilities, but few associations between neuroanatomic abnormalities and reading problems have been found. We examined the neuronal bases for phonologic processing, a core component...