John M Slopis
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Explore the profile of John M Slopis including associated specialties, affiliations and a list of published articles.
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35
Citations
832
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Recent Articles
11.
Koczkowska M, Callens T, Chen Y, Gomes A, Hicks A, Sharp A, et al.
Hum Mutat
. 2019 Oct;
41(1):299-315.
PMID: 31595648
We report 281 individuals carrying a pathogenic recurrent NF1 missense variant at p.Met1149, p.Arg1276, or p.Lys1423, representing three nontruncating NF1 hotspots in the University of Alabama at Birmingham (UAB) cohort,...
12.
Slopis J, Arevalo O, Bell C, Hebert A, Northrup H, Riascos R, et al.
Drugs R D
. 2018 Oct;
18(4):295-302.
PMID: 30284154
Background: Cutaneous neurofibromas cause disfigurement and discomfort in individuals with neurofibromatosis type 1 (NF-1). Methods: The primary objective of this phase II, open-label, single-arm trial was to assess whether orally...
13.
Mahadeo K, Khazal S, Abdel-Azim H, Fitzgerald J, Taraseviciute A, Bollard C, et al.
Nat Rev Clin Oncol
. 2018 Aug;
16(1):45-63.
PMID: 30082906
In 2017, an autologous chimeric antigen receptor (CAR) T cell therapy indicated for children and young adults with relapsed and/or refractory CD19 acute lymphoblastic leukaemia became the first gene therapy...
14.
Koenig M, Bell C, Hebert A, Roberson J, Samuels J, Slopis J, et al.
JAMA Dermatol
. 2018 May;
154(7):773-780.
PMID: 29800048
Importance: Facial angiofibromas occur in approximately 75% of individuals with tuberous sclerosis complex (TSC), causing substantial morbidity and disfigurement. Current therapies are partially effective, uncomfortable, produce scarring, and need repeating...
15.
Jittapiromsak N, Hou P, Liu H, Sun J, Slopis J, Chi T
J Neuroimaging
. 2017 May;
27(6):594-601.
PMID: 28524459
Background And Purpose: The natural history of optic pathway glioma (OPG) is highly variable and unpredictable. We present a pilot study of the prognostic role of conventional and dynamic contrast-enhanced...
16.
Watson K, Sannaa G, Kivlin C, Ingram D, Landers S, Roland C, et al.
J Neurosurg
. 2016 Apr;
126(1):319-329.
PMID: 27035165
OBJECTIVE Malignant peripheral nerve sheath tumors (MPNSTs) are an aggressive group of soft tissue sarcomas that can arise sporadically, in the context of neurofibromatosis Type 1 (NF1) or at a...
17.
Z Ghali M, Srinivasan V, Jea A, Slopis J, McCutcheon I
World Neurosurg
. 2016 Jan;
88:237-242.
PMID: 26746336
Background: Phrenic neurofibromas are a rare pathologic entity, with 9 cases described in the English literature. They may occur in conjunction with or independently of neurofibromatosis type 1. Phrenic neurofibromas...
18.
Kivlin C, Watson K, Sannaa G, Belousov R, Ingram D, Huang K, et al.
Cancer Biol Ther
. 2015 Dec;
17(2):129-38.
PMID: 26650448
Poly (ADP) ribose polymerase (PARP) inhibitors, first evaluated nearly a decade ago, are primarily used in malignancies with known defects in DNA repair genes, such as alterations in breast cancer,...
19.
Debnam J, Mahfouz Y, Ketonen L, Slopis J, McCutcheon I, Guha-Thakurta N
Scoliosis
. 2015 Apr;
9:15.
PMID: 25852768
Introduction: Neurofibromatosis type 1 (NF-1) may involve the spine as various abnormalities including bony dysplasia, scoliosis, and nerve sheath tumors. Surgery may be performed for stabilization of the spine. We...
20.
Theeler B, Ellezam B, Yust-Katz S, Slopis J, Loghin M, de Groot J
J Neurol
. 2014 May;
261(8):1559-64.
PMID: 24859329
Astrocytic tumors, especially optic pathway pilocytic astrocytomas, are common in pediatric NF1 patients. High-grade gliomas (HGGs) appear to be rare in adult and pediatric NF1 patients. This is a series...