John M C Connell
Overview
Explore the profile of John M C Connell including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
59
Citations
2055
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Mooij C, Parajes S, Rose I, Taylor A, Bayraktaroglu T, Wass J, et al.
Clin Endocrinol (Oxf)
. 2015 Jun;
83(5):629-35.
PMID: 26053152
Objective: Steroid 11β-hydroxylase (CYP11B1) deficiency (11OHD) is the second most common form of congenital adrenal hyperplasia. Nonclassic or mild 11OHD appears to be a rare condition. Our study assessed the...
2.
Terao C, Bayoumi N, Mckenzie C, Zelenika D, Muro S, Mishima M, et al.
Ann Hum Genet
. 2013 Aug;
77(6):465-71.
PMID: 23937567
Angiotensin-I converting enzyme (ACE) occupies a pivotal role in cardiovascular homeostasis. Major loci for plasma ACE have been identified at ACE on Chromosome 17 and at ABO on Chromosome 9....
3.
McQuarrie E, Freel E, Mark P, Fraser R, Connell J, Jardine A
Nephrol Dial Transplant
. 2013 Feb;
28(6):1526-32.
PMID: 23413088
Background: Blockade of the mineralocorticoid receptor (MR) in patients with chronic kidney disease (CKD) improves surrogate cardiovascular outcomes, such as left ventricular mass. Animal models of renal disease support a...
4.
Freel E, Mark P, Weir R, McQuarrie E, Allan K, Dargie H, et al.
Circ Cardiovasc Imaging
. 2012 Sep;
5(6):740-7.
PMID: 23019275
Background: Primary aldosteronism (PA) is common and associates with excess cardiovascular morbidity independent of blood pressure. Exposure to aldosterone and sodium leads to cardiac fibrosis and hypertrophy in humans and...
5.
McQuarrie E, Freel E, Mark P, Fraser R, Patel R, Dargie H, et al.
Clin Sci (Lond)
. 2012 Mar;
123(5):285-94.
PMID: 22397469
Blockade of the MR (mineralocorticoid receptor) in CKD (chronic kidney disease) reduces LVMI [LV (left ventricular) mass index] and proteinuria. The MR can be activated by aldosterone, cortisol and DOC...
6.
Weir R, Tsorlalis I, Steedman T, Dargie H, Fraser R, McMurray J, et al.
Eur J Heart Fail
. 2011 Sep;
13(12):1305-13.
PMID: 21940729
Aims: Mineralocorticoid receptor (MR) antagonists improve cardiovascular outcomes in patients with heart failure complicating acute myocardial infarction (AMI) and in chronic heart failure. It is unclear whether these beneficial effects...
7.
Kohlhaas C, Morrow V, Jhakra N, Patil V, Connell J, Petrie J, et al.
Biochem Biophys Res Commun
. 2011 Aug;
412(4):747-51.
PMID: 21871446
Insulin stimulates endothelial NO synthesis, at least in part mediated by phosphorylation and activation of endothelial NO synthase at Ser1177 and Ser615 by Akt. We have previously demonstrated that insulin-stimulated...
8.
Rahman T, Walker E, Mayosi B, Hall D, Avery P, Connell J, et al.
PLoS One
. 2011 Aug;
6(8):e23248.
PMID: 21858044
Objective: The combined thickness of the intima and media of the carotid artery (carotid intima-medial thickness, CIMT) is associated with cardiovascular disease and stroke. Previous studies indicate that carotid intima-medial...
9.
MacKenzie S, Connell J, Davies E
Mol Cell Endocrinol
. 2011 Jul;
350(2):163-7.
PMID: 21767599
Advances in the sensitivity of molecular techniques during the 1990s led to a flurry of studies that supported the existence of extra-adrenal sites of aldosterone production in various tissues including...
10.
Rahman T, Mayosi B, Hall D, Avery P, Stewart P, Connell J, et al.
Circ Cardiovasc Genet
. 2011 Mar;
4(2):156-62.
PMID: 21402901
Background: Polymorphisms in 11-β hydroxysteroid dehydrogenase type 1 (11β-HSD1, encoded by HSD11B1) have been reported to be associated with obesity-related cardiovascular risk factors, such as type II diabetes and hypertension....