John L Morrison
Overview
Explore the profile of John L Morrison including associated specialties, affiliations and a list of published articles.
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13
Citations
222
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Recent Articles
1.
Noordam R, Wang W, Nagarajan P, Wang H, Brown M, Bentley A, et al.
medRxiv
. 2024 Sep;
PMID: 39281768
We performed large-scale genome-wide gene-sleep interaction analyses of lipid levels to identify novel genetic variants underpinning the biomolecular pathways of sleep-associated lipid disturbances and to suggest possible druggable targets. We...
2.
Nagarajan P, Winkler T, Bentley A, Miller C, Kraja A, Schwander K, et al.
medRxiv
. 2024 Mar;
PMID: 38496537
Although both short and long sleep duration are associated with elevated hypertension risk, our understanding of their interplay with biological pathways governing blood pressure remains limited. To address this, we...
3.
Stern M, Sanchez Mendez J, Kim A, Obon-Santacana M, Moratalla-Navarro F, Martin V, et al.
Cancer Epidemiol Biomarkers Prev
. 2023 Dec;
33(3):400-410.
PMID: 38112776
Background: High red meat and/or processed meat consumption are established colorectal cancer risk factors. We conducted a genome-wide gene-environment (GxE) interaction analysis to identify genetic variants that may modify these...
4.
Shrine N, Izquierdo A, Chen J, Packer R, Hall R, Guyatt A, et al.
Nat Genet
. 2023 Sep;
55(10):1778-1779.
PMID: 37749248
No abstract available.
5.
Shrine N, Izquierdo A, Chen J, Packer R, Hall R, Guyatt A, et al.
Nat Genet
. 2023 Mar;
55(3):410-422.
PMID: 36914875
Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of lung function to date, comprising 580,869 participants, we identified 1,020 independent...
6.
Carreras-Torres R, Kim A, Lin Y, Diez-Obrero V, Bien S, Qu C, et al.
Cancer Epidemiol Biomarkers Prev
. 2022 Dec;
32(3):315-328.
PMID: 36576985
Background: Tobacco smoking is an established risk factor for colorectal cancer. However, genetically defined population subgroups may have increased susceptibility to smoking-related effects on colorectal cancer. Methods: A genome-wide interaction...
7.
Jordahl K, Shcherbina A, Kim A, Su Y, Lin Y, Wang J, et al.
Cancer Epidemiol Biomarkers Prev
. 2022 Apr;
31(5):1077-1089.
PMID: 35438744
Background: Currently known associations between common genetic variants and colorectal cancer explain less than half of its heritability of 25%. As alcohol consumption has a J-shape association with colorectal cancer...
8.
Zhang P, Lewinger J, Conti D, Morrison J, Gauderman W
Genet Epidemiol
. 2016 May;
40(5):394-403.
PMID: 27230133
A genome-wide association study (GWAS) typically is focused on detecting marginal genetic effects. However, many complex traits are likely to be the result of the interplay of genes and environmental...
9.
Gauderman W, Zhang P, Morrison J, Lewinger J
Genet Epidemiol
. 2013 Jul;
37(6):603-13.
PMID: 23873611
In a genome-wide association study (GWAS), investigators typically focus their primary analysis on the direct (marginal) associations of each single nucleotide polymorphism (SNP) with the trait. Some SNPs that are...
10.
Lewinger J, Morrison J, Thomas D, Murcray C, Conti D, Li D, et al.
Genet Epidemiol
. 2013 May;
37(5):440-51.
PMID: 23633124
Exhaustive testing of all possible SNP pairs in a genome-wide association study (GWAS) generally yields low power to detect gene-gene (G × G) interactions because of small effect sizes and...