John J Wysolmerski
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Explore the profile of John J Wysolmerski including associated specialties, affiliations and a list of published articles.
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38
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1267
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Recent Articles
1.
Niu I, Hsiao E, Wustrack R, Wysolmerski J, Dann P, Masharani U
Calcif Tissue Int
. 2023 Jun;
113(2):246-253.
PMID: 37358786
The treatment of parathyroid hormone-related protein (PTHrP)-mediated hypercalcemia of malignancy includes treating the malignancy, intravenous fluids, and anti-resorptive therapies such as zoledronic acid or denosumab. PTHrP-mediated hypercalcemia has been reported...
2.
Crosstalk within a brain-breast-bone axis regulates mineral and skeletal metabolism during lactation
Athonvarangkul D, Wysolmerski J
Front Physiol
. 2023 Mar;
14:1121579.
PMID: 36875035
To support the increased calcium demands for milk production during lactation, a dramatic and reversible physiological response occurs to alter bone and mineral metabolism. This coordinated process involves a brain-breast-bone...
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Grinman D, Boras-Granic K, Takyar F, Dann P, Hens J, Marmol C, et al.
Breast Cancer Res
. 2022 Apr;
24(1):30.
PMID: 35440032
Background: Parathyroid hormone-related protein (PTHrP) is required for embryonic breast development and has important functions during lactation, when it is produced by alveolar epithelial cells and secreted into the maternal...
5.
Guise T, Wysolmerski J
N Engl J Med
. 2022 Apr;
386(15):1443-1451.
PMID: 35417639
No abstract available.
6.
Jeong J, Kadegowda A, Meyer T, Jenkins L, Dinan J, Wysolmerski J, et al.
FASEB Bioadv
. 2021 Dec;
3(12):971-997.
PMID: 34938960
Butyrophilin 1A1 (BTN1A1) is implicated in the secretion of lipid droplets from mammary epithelial cells as a membrane receptor, which forms a secretion complex with the redox enzyme, xanthine oxidoreductase...
7.
Jeong J, Kim W, Hens J, Dann P, Schedin P, Friedman P, et al.
Endocrinology
. 2019 May;
160(8):1797-1810.
PMID: 31087002
Prior studies have demonstrated that the calcium pump, plasma membrane calcium ATPase 2 (PMCA2), mediates calcium transport into milk and prevents mammary epithelial cell death during lactation. PMCA2 also regulates...
8.
Jeong J, Choi J, Kim W, Dann P, Takyar F, Gefter J, et al.
J Biol Chem
. 2018 Nov;
294(3):887-901.
PMID: 30463939
Unlike other ErbB family members, HER2 levels are maintained on the cell surface when the receptor is activated, allowing prolonged signaling and contributing to its transforming ability. Interactions between HER2,...
9.
Jeong J, Kim W, Kim L, VanHouten J, Wysolmerski J
PLoS One
. 2017 Apr;
12(4):e0174849.
PMID: 28369073
ErbB2/HER2/Neu is a receptor tyrosine kinase that is overexpressed in 25-30% of human breast cancers, usually associated with amplification of the ERBB2 gene. HER2 has no recognized ligands and heterodimers...
10.
Jeong J, VanHouten J, Kim W, Dann P, Sullivan C, Choi J, et al.
J Biol Chem
. 2017 Feb;
292(16):6555-6568.
PMID: 28235801
We examined whether the scaffolding protein sodium-hydrogen exchanger regulatory factor 1 (NHERF1) interacts with the calcium pump PMCA2 and the tyrosine kinase receptor ErbB2/HER2 in normal mammary epithelial cells and...