John I Harper
Overview
Explore the profile of John I Harper including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
32
Citations
1058
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0
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Recent Articles
1.
Tagoe H, Hassan S, Bliss E, Youssef G, Heywood W, Mills K, et al.
Br J Dermatol
. 2023 Mar;
189(1):91-102.
PMID: 36972303
Background: Ichthyosis defines a group of chronic conditions that manifest phenotypically as a thick layer of scales, often affecting the entire skin. While the gene mutations that lead to ichthyosis...
2.
Chan S, Cornelius V, Cro S, Harper J, Lack G
JAMA Pediatr
. 2019 Nov;
174(1):29-37.
PMID: 31764962
Importance: Systemic treatments for severe childhood atopic dermatitis have limited evidence and/or are unlicensed. Despite the efficacy of anti-IgE medication (omalizumab) in the treatment of atopy, no large randomized studies...
3.
Di W, Lwin S, Petrova A, Bernadis C, Syed F, Farzaneh F, et al.
Hum Gene Ther
. 2019 Jul;
30(9):1067-1078.
PMID: 31288584
Netherton syndrome (NS) is a rare autosomal recessive skin disorder caused by mutations in . It is a debilitating condition with notable mortality in the early years of life. There...
4.
Zhu Y, Underwood J, Macmillan D, Shariff L, OShaughnessy R, Harper J, et al.
J Allergy Clin Immunol
. 2017 Feb;
140(5):1310-1322.e5.
PMID: 28238749
Background: Upregulation of kallikreins (KLKs) including KLK5 has been reported in atopic dermatitis (AD). KLK5 has biological functions that include degrading desmosomal proteins and inducing proinflammatory cytokine secretion through protease-activated...
5.
Leaute-Labreze C, Harper J, Hoeger P
Lancet
. 2017 Jan;
390(10089):85-94.
PMID: 28089471
With a prevalence of 4·5%, infantile haemangiomas are the most common benign tumours of infancy, arising in the first few weeks of life and exhibiting a characteristic sequence of growth...
6.
Naeem A, Tommasi C, Cole C, Brown S, Zhu Y, Way B, et al.
J Allergy Clin Immunol
. 2016 Dec;
139(4):1228-1241.
PMID: 27913303
Background: Filaggrin, which is encoded by the filaggrin gene (FLG), is an important component of the skin's barrier to the external environment, and genetic defects in FLG strongly associate with...
7.
Hoeger P, Harper J, Baselga E, Bonnet D, Boon L, Ciofi Degli Atti M, et al.
Eur J Pediatr
. 2015 May;
174(7):855-65.
PMID: 26021855
Unlabelled: With a prevalence of 2.6-4.5 %, infantile haemangiomas (IH) represent the most common tumour of infancy. While the majority of IH does not require therapy and regresses spontaneously, about...
8.
Solman L, Murabit A, Gnarra M, Harper J, Syed S, Glover M
Arch Dis Child
. 2014 Aug;
99(12):1132-6.
PMID: 25123404
Objective: To assess the safety and efficacy of systemic propranolol for the treatment of complicated infantile haemangiomas. Design: Retrospective review of case notes of paediatric patients treated with propranolol for...
9.
Campbell P, Morton P, Takeichi T, Salam A, Roberts N, Proudfoot L, et al.
J Invest Dermatol
. 2014 Apr;
134(10):2570-2578.
PMID: 24691054
Epidermal growth factor receptor (EGFR) signaling is fundamentally important for tissue homeostasis through EGFR/ligand interactions that stimulate numerous signal transduction pathways. Aberrant EGFR signaling has been reported in inflammatory and...
10.
Youssef G, Ono M, Brown S, Kinsler V, Sebire N, Harper J, et al.
J Invest Dermatol
. 2013 Sep;
134(3):858-861.
PMID: 24005053
No abstract available.